Glud1 - glutamate dehydrogenase 1 Gene

Also Known as Gdh1; Glud; MRG-2; Ac2-281; Gludeha

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 24399

Summary

Enables enzyme binding activity and glutamate dehydrogenase (NAD+) activity. Involved in cerebellum development; long-term memory; and response to aluminum ion. Located in mitochondrion. Biomarker of brain disease (multiple) and fascioliasis. Human ortholog(s) of this gene implicated in familial hyperinsulinemic hypoglycemia 6; hyperinsulinism; hypoglycemia; and late onset Parkinson's disease. Orthologous to several human genes including GLUD1 (glutamate dehydrogenase 1). [provided by Alliance of Genome Resources, Apr 2022]

Glud1 Products (1)

mRNA Protein Name
NM_012570.2 NP_036702.1 glutamate dehydrogenase 1, mitochondrial precursor

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables enzyme binding IPI
IPI: Inferred from physical interaction
1684101 RGD
enables glutamate dehydrogenase (NAD+) activity IDA
IDA: Inferred from direct assay
15273247 RGD
Biological Process GO Annotation Evidence References Source
involved in cerebellum development IEP
IEP: Inferred from expression pattern
7182074 RGD
involved in long-term memory IEP
IEP: Inferred from expression pattern
9275181 RGD
involved in response to aluminum ion IDA
IDA: Inferred from direct assay
10806405 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

glutamate dehydrogenase 1, mitochondrial

  • memory-related gene 2 protein

Related Agents

  • Clinical Phase
  • Pre-clinical Phase

Clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Phase
HY-150526 EGCG-4″-sulfate Inducer / Phase 4

Pre-clinical Phase

Bioactive Molecules (9)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-13653 (-)-Epigallocatechin Gallate Inducer 99.75% Yes
HY-103096 R162 Inhibitor 99.89% Unkown
HY-13653R (-)-Epigallocatechin Gallate (Standard) Inducer 98.05% Unkown
HY-13653S1 (-)-Epigallocatechin Gallate-d4 Inducer 97.14% Unkown
HY-RS05507 GLUD1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS05795 GRID1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-170017S (−)-Epigallocatechin Gallate-d3/d4 Inducer / Unkown
HY-RS17659 Glud1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS24120 Glud1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Glud1 NCBI NCBI:2746