Lypla1 - lysophospholipase 1 Gene

Also Known as 25KDL; Pla1a

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 25514

Summary

Enables lysophospholipase activity. Predicted to be involved in protein depalmitoylation. Predicted to act upstream of or within negative regulation of Golgi to plasma membrane protein transport. Predicted to be located in several cellular components, including cytosol; endoplasmic reticulum; and nuclear membrane. Predicted to be active in cytoplasm. Orthologous to human LYPLA1 (lysophospholipase 1). [provided by Alliance of Genome Resources, Apr 2022]

Lypla1 Products (1)

mRNA Protein Name
NM_013006.2 NP_037138.1 acyl-protein thioesterase 1

Gene Ontology

  • Molecular Function
Molecular Function GO Annotation Evidence References Source
enables lysophospholipase activity IDA
IDA: Inferred from direct assay
9644627 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

acyl-protein thioesterase 1

  • APT-1

  • LPL-I

  • lysoPLA I

  • lysophospholipase I

  • palmitoyl-protein hydrolase

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (7)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-100736 ML348 Inhibitor 99.97% Unkown
HY-128035 ML-211 Inhibitor 99.42% Unkown
HY-129121 ML-​226 Inhibitor 98.76% Unkown
HY-120126 ML378 Inhibitor / Unkown
HY-RS07921 LYPLA1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS17852 Lypla1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS24321 Lypla1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Lypla1 NCBI NCBI:10434