1. Metabolic Enzyme/Protease
  2. Phospholipase
    MAGL
  3. ML-211

ML-211 

Cat. No.: HY-128035
Handling Instructions

ML-211 is a carbamate-based dual inhibitor of acyl-protein thioesterase 1 (APT1)/lysophospholipase 1 (LYPLA1) (IC50=17 nM) and LYPLA2 (IC50=30 nM). ML-211 also inhibits theserine hydrolase ABHD11 with an IC50 value of 10 nM but is ≥ 50-fold selective for LYPLA in a panel of 20 additional serine hydrolases.

For research use only. We do not sell to patients.

ML-211 Chemical Structure

ML-211 Chemical Structure

CAS No. : 2205032-89-7

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Description

ML-211 is a carbamate-based dual inhibitor of acyl-protein thioesterase 1 (APT1)/lysophospholipase 1 (LYPLA1) (IC50=17 nM) and LYPLA2 (IC50=30 nM). ML-211 also inhibits theserine hydrolase ABHD11 with an IC50 value of 10 nM but is ≥ 50-fold selective for LYPLA in a panel of 20 additional serine hydrolases[1].

Molecular Weight

418.53

Formula

C25H30N4O2

CAS No.
SMILES

O=C(N1CCC(C(C)(C)C)CC1)N2N=CC(C(C3=CC=CC=C3)(O)C4=CC=CC=C4)=N2

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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ML-211
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HY-128035
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