2205032-89-7
2205032-89-7
Chemical Structure
ML-211
- CAS No.: 2205032-89-7
- Formula:C25H30N4O2
- Molecular Weight:418.53
IUPAC Name: (4-(tert-butyl)piperidin-1-yl)(4-(hydroxydiphenylmethyl)-2H-1,2,3-triazol-2-yl)methanone
InChIKey: LPTMHNPBMQCQPG-UHFFFAOYSA-N
SMILES: O=C(N1CCC(C(C)(C)C)CC1)N2N=CC(C(C3=CC=CC=C3)(O)C4=CC=CC=C4)=N2
Biological Activity: ML-211 is a potent dual inhibitor of LYPLA1 and LYPLA2 enzymes, with an IC50 value of 17 nM against LYPLA1, 30 nM against LYPLA2, and 10 nM against ABHD11[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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ML-211 | 99.42% | ML-211 is a potent dual inhibitor of LYPLA1 and LYPLA2 enzymes, with an IC50 value of 17 nM against LYPLA1, 30 nM against LYPLA2, and 10 nM against ABHD11. | ||||||||||||||||||||
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References
- [1]. Adibekian A, et al. Optimization and characterization of a triazole urea dual inhibitor for lysophospholipase 1 (LYPLA1) and lysophospholipase 2 (LYPLA2). 2011 Feb 25 [updated 2013 Mar 7]. In: Probe Reports from the NIH Molecular Libraries Program [Internet]. Bethesda (MD): National Center for Biotechnology Information (US); 2010–. [Content Brief]
Keywords
