Agrp - agouti related neuropeptide Gene

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 25582

Summary

Predicted to enable neuropeptide hormone activity and type 1 Melanocortin Receptor binding activity. Involved in several processes, including adult feeding behavior; neuropeptide signaling pathway; and positive regulation of feeding behavior. Located in extracellular space and neuronal cell body. Biomarker of obesity and type 2 diabetes mellitus. Human ortholog(s) of this gene implicated in obesity and type 2 diabetes mellitus. Orthologous to human AGRP (agouti related neuropeptide). [provided by Alliance of Genome Resources, Apr 2022]

Agrp Products (1)

mRNA Protein Name
NM_033650.1 NP_387499.1 agouti-related protein precursor

Gene Ontology

  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence References Source
involved in adult feeding behavior IEP
IEP: Inferred from expression pattern
22425130 RGD
involved in circadian rhythm IEP
IEP: Inferred from expression pattern
21060311 RGD
involved in eating behavior IMP
IMP: Inferred from mutant phenotype
16604086 RGD
involved in long-day photoperiodism IEP
IEP: Inferred from expression pattern
19490367 RGD
involved in maternal process involved in female pregnancy IEP
IEP: Inferred from expression pattern
21303957 RGD
involved in neuropeptide signaling pathway IEP
IEP: Inferred from expression pattern
10875247 RGD
involved in positive regulation of feeding behavior IDA
IDA: Inferred from direct assay
21527895 RGD
involved in positive regulation of feeding behavior IMP
IMP: Inferred from mutant phenotype
20551287 RGD
involved in response to insulin IEP
IEP: Inferred from expression pattern
11179781 RGD
Cellular Component GO Annotation Evidence References Source
located in extracellular space IDA
IDA: Inferred from direct assay
19632697 RGD
located in neuronal cell body IDA
IDA: Inferred from direct assay
20736052 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

agouti-related protein

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (7)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-116797 MS15203 99.40% Unkown
HY-P3561A Agouti-related Protein (AGRP) (83-132) Amide (human) TFA Inhibitor 98.30% Unkown
HY-P3561 Agouti-related Protein (AGRP) (83-132) Amide (human) Antagonist / Unkown
HY-P3924 Agouti-Related Protein (54-82) (human) Inhibitor / Unkown
HY-RS00465 AGRP Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS17733 Agrp Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS24198 Agrp Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Agrp NCBI NCBI:181