Selp - selectin P Gene

Also Known as PSELECT

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 25651

Summary

Predicted to enable several functions, including fucose binding activity; heparin binding activity; and lipopolysaccharide binding activity. Involved in several processes, including leukocyte migration; regulation of cellular extravasation; and response to lipopolysaccharide. Located in external side of plasma membrane and extracellular space. Used to study acute necrotizing pancreatitis and anti-basement membrane glomerulonephritis. Biomarker of atherosclerosis; colitis; congestive heart failure; and myocardial infarction. Human ortholog(s) of this gene implicated in atopic dermatitis and myocardial infarction. Orthologous to human SELP (Selectin P). [provided by Alliance of Genome Resources, Apr 2022]

Selp Products (1)

mRNA Protein Name
NM_013114.2 NP_037246.2 P-selectin precursor

Gene Ontology

  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence References Source
involved in cell-cell adhesion IMP
IMP: Inferred from mutant phenotype
14963004 RGD
involved in leukocyte migration IMP
IMP: Inferred from mutant phenotype
12377736 RGD
involved in positive regulation of cell adhesion IMP
IMP: Inferred from mutant phenotype
19451746 RGD
involved in regulation of cellular extravasation IMP
IMP: Inferred from mutant phenotype
12081568 RGD
involved in response to lipopolysaccharide IEP
IEP: Inferred from expression pattern
7520013 RGD
involved in response to organic cyclic compound IEP
IEP: Inferred from expression pattern
18095572 RGD
Cellular Component GO Annotation Evidence References Source
located in external side of plasma membrane IDA
IDA: Inferred from direct assay
14963004 RGD
located in extracellular space IDA
IDA: Inferred from direct assay
18471420 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

P-selectin

  • CD62 antigen-like family member P

  • GMP-140

  • LECAM3

  • PADGEM

  • granule membrane protein 140

  • leukocyte-endothelial cell adhesion molecule 3

  • platelet activation dependent granule-external membrane protein

  • selectin, platelet

Recombinant Selp Proteins

Cat. No. Product Name Accession Purity
HY-P73385 P-Selectin Protein, Rat (HEK293, Fc) P98106/AAI01920.1 (W42-Q700) ≥ 95%, as determined by reducing SDS-PAGE.
HY-P73689 P-Selectin Protein, Rat (HEK293, His) P98106/AAI01920.1 (W42-Q700) ≥ 95%, as determined by reducing SDS-PAGE.

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (5)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS12641 SELENOP Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS12647 SELP Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS17272 Selp Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS18579 Selenop Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS23726 Selp Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Selp NCBI NCBI:6403