Map3k8 - mitogen-activated protein kinase kinase kinase 8 Gene
Also Known as Cot; Est; Estf; Tpl2; Tpl-2; c-COT; Cot/Tpl2
Species: Mus musculus
About Map3k8
This gene has 5 transcripts (splice variants), 199 orthologues, 35 paralogues and is associated with 34 phenotypes. Ubiquitous expression in spleen adult (RPKM 3.1), lung adult (RPKM 2.9) and 27 other tissues.
Summary
Predicted to enable MAP kinase kinase kinase activity. Predicted to be involved in protein phosphorylation and signal transduction. Predicted to act upstream of or within immune system process and phosphorylation. Predicted to be located in cytosol. Is expressed in several structures, including adipose tissue; adrenal gland; alimentary system; hemolymphoid system gland; and reproductive system. Orthologous to human MAP3K8 (mitogen-activated protein kinase kinase kinase 8). [provided by Alliance of Genome Resources, Apr 2022]
Map3k8 Products (1)
| mRNA | Protein | Name |
|---|---|---|
| NM_007746.2 | NP_031772.1 | mitogen-activated protein kinase kinase kinase 8 |
Map3k8 Protein Structure
STKc_MAP3K8: cd13995 (132 - 387)
- 0
- 100
- 200
- 300
- 400
- 467 a.a.
| Protein Preferred Names | Protein Names | |
|---|---|---|
|
mitogen-activated protein kinase kinase kinase 8 |
|
|
Related Agents
- Pre-clinical Phase
Pre-clinical Phase
| Cat. No. | Product Name |
Effect
|
Purity |
Rare Diseases
|
|---|---|---|---|---|
| HY-12358 | Tpl2 Kinase Inhibitor 1 | Inhibitor | 99.42% | Unkown |
| HY-124953 | 7,3',4'-Trihydroxyisoflavone | 99.83% | Unkown | |
| HY-32018 | Cot inhibitor-2 | Inhibitor | 99.65% | Unkown |
| HY-RS08067 | Map3k8 Mouse Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
| HY-RS08068 | Map3k8 Rat Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
| HY-12358A | Tpl2 Kinase Inhibitor 1 hydrochloride | Inhibitor | / | Unkown |
| HY-RS08066 | MAP3K8 Human Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
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