Racgap1 - Rac GTPase-activating protein 1 Gene

Also Known as gtl11; Band25; GTPase; MgcRacGAP; mKIAA1478

Species: Mus musculus

Gene Type: protein coding
Gene ID: 26934

Summary

Predicted to enable several functions, including GTPase activator activity; phosphatidylinositol-3,4,5-trisphosphate binding activity; and tubulin binding activity. Involved in regulation of embryonic development. Acts upstream of or within neuroblast proliferation. Predicted to be located in several cellular components, including cleavage furrow; midbody; and spindle. Predicted to be extrinsic component of cytoplasmic side of plasma membrane. Predicted to be part of centralspindlin complex. Is expressed in several structures, including blastocyst; central nervous system; early embryo; neural retina; and nose. Orthologous to human RACGAP1 (Rac GTPase activating protein 1). [provided by Alliance of Genome Resources, Apr 2022]

Racgap1 Products (5)

mRNA Protein Name
NM_001253808.2 NP_001240737.1 rac GTPase-activating protein 1
NM_001253809.2 NP_001240738.1 rac GTPase-activating protein 1
NM_001411865.1 NP_001398794.1 rac GTPase-activating protein 1
NM_001411866.1 NP_001398795.1 rac GTPase-activating protein 1
NM_012025.8 NP_036155.1 rac GTPase-activating protein 1
Biological Process GO Annotation Evidence References Source
involved in neuroblast proliferation IEP
IEP: Inferred from expression pattern
10493933 MGI
involved in regulation of embryonic development IMP
IMP: Inferred from mutant phenotype
11287179 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

rac GTPase-activating protein 1

  • male germ cell RacGap

Orthologs Information

Species Symbol Source ID
Homo sapiens Racgap1 NCBI NCBI:29127