IL17B - interleukin 17B Gene

Also Known as NIRF; IL-20; IL-17B; ZCYTO7

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 27190

About IL17B

Cytogenetic location: 5q32 Genomic coordinates (GRCh38): 5:149,374,267-149,404,202 (from NCBI)

This gene has 3 transcripts (splice variants), 137 orthologues and 5 paralogues. Low expression observed in reference dataset.

Summary

The protein encoded by this gene is a T cell-derived cytokine that shares sequence similarity with IL17. This cytokine was reported to stimulate the release of TNF alpha (TNF) and IL1 beta (IL1B) from a monocytic cell line. Immunohistochemical analysis of several nerve tissues indicated that this cytokine is primarily localized to neuronal cell bodies. Alternative splicing results in multiple splice variants. [provided by RefSeq, Dec 2015]

IL17B Products (2)

mRNA Protein Name
NM_001317987.2 NP_001304916.1 interleukin-17B isoform 2
NM_014443.3 NP_055258.1 interleukin-17B isoform 1 precursor

IL17B Protein Structure

IL17

IL17: Interleukin-17 (95 - 180)

  • 0
  • 100
  • 180 a.a.
Protein Preferred Names Protein Names

interleukin-17B

  • cytokine-like protein ZCYTO7

Recombinant IL17B Proteins

Cat. No. Product Name Accession Purity
HY-P71856 IL-17B Protein, Human Q9UHF5 (Q21-F180) ≥ 95%, as determined by reducing SDS-PAGE.
HY-P72588 IL-17B Protein, Human (HEK293, Fc) Q9UHF5 (Q21-F180) ≥ 95%, as determined by reducing SDS-PAGE.
HY-P700105AF Animal-Free IL-17B Protein, Human (His) Q9UHF5 (Q21-F180) ≥ 95%, as determined by reducing SDS-PAGE.

Related Diseases

Diseases Alias
Leiomyoma

  • Leiomyomatous Neoplasm

  • Leiomyomatous Tumor

  • Leiomyomas

  • Fibroid Tumor

  • Uterine Fibroids
Psoriasis
Rheumatoid Arthritis

  • RA

  • Arthritis, Rheumatoid

  • Rheumatoid Arthritis, Susceptibility To

  • Arthritis Or Polyarthritis, Rheumatic

  • Atrophic Arthritis

  • Rheumatism Arthritis

  • Rheumatoid Polyarthritis
Systemic Lupus Erythematosus

  • Lupus Nephritis

  • SLE

  • Disseminated Lupus Erythematosus

  • Systemic Lupus Erythematosus, Susceptibility To

  • Lupus Erythematosus, Systemic

  • Lupus Nephritis, Susceptibility To

  • Libman-Sacks Disease

  • Systemic Lupus Erythematosus Susceptibility To

  • Sle - Lupus Erythematosus, Systemic

  • Le Syndrome

  • Lupus

  • Lupus Erythematosus Systemic

  • Lupus Erythematosus, Systemic, Susceptibility To

  • Lupus Vulgaris

  • Lupus Erythematosus, Discoid

  • Lupus Erythematosus

  • Systemic Lupus Erythematosus Nos

  • Sle - [Systemic Lupus Erythematosus]
Chronic Mucocutaneous Candidiasis

  • Candidiasis, Chronic Mucocutaneous

  • Cmc

  • Candidiasis Chronic Mucocutaneous
Charcot-Marie-Tooth Disease

  • Cmt

  • Hmsn

  • Hereditary Motor And Sensory Neuropathy

  • Pma

  • Cmt - Charcot-Marie-Tooth Disease

  • Charcot Marie Tooth Disease

  • Charcot-Marie-Tooth Hereditary Neuropathy

  • Charcot-Marie-Tooth Syndrome

  • Peroneal Muscular Atrophy

  • Hereditary Motor And Sensory Neuropathies
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Clinical Phase
  • Pre-clinical Phase

Clinical Phase

Inhibitory Antibodies (1)
Cat. No. Product Name Effect
Purity Phase
HY-P990741 Galvokimig 98.74% Phase 2

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS06698 IL17B Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Felis catus IL17B VGNC VGNC:102232
Canis familiaris IL17B VGNC VGNC:41943
Bos taurus IL17B VGNC VGNC:30118
Mus musculus IL17B MGD MGI:1928397
Macaca mulatta IL17B VGNC VGNC:110458
Rattus norvegicus IL17B RGD RGD:620614
Others IL17B NCBI