Taok1 - TAO kinase 1 Gene

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 286993

Summary

Enables several functions, including Myosin V binding activity; protein C-terminus binding activity; and protein serine/threonine kinase activator activity. Involved in protein autophosphorylation; regulation of actin Cytoskeleton organization; and regulation of microtubule Cytoskeleton organization. Predicted to be located in microtubule Cytoskeleton and perinuclear region of cytoplasm. Predicted to be active in cytoplasm. Orthologous to human TAOK1 (TAO kinase 1). [provided by Alliance of Genome Resources, Apr 2022]

Taok1 Products (1)

mRNA Protein Name
NM_173327.2 NP_775449.2 serine/threonine-protein kinase TAO1

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables myosin V binding IPI
IPI: Inferred from physical interaction
24478457 RGD
enables protein binding IPI
IPI: Inferred from physical interaction
18216281 RGD
enables protein kinase activator activity IMP
IMP: Inferred from mutant phenotype
9786855 RGD
enables protein kinase activity IDA
IDA: Inferred from direct assay
18216281 RGD
enables protein kinase binding IDA
IDA: Inferred from direct assay
9786855 RGD
enables protein kinase binding IPI
IPI: Inferred from physical interaction
18216281 RGD
enables protein serine/threonine kinase activator activity IDA
IDA: Inferred from direct assay
14517247 RGD
enables protein serine/threonine kinase activity IDA
IDA: Inferred from direct assay
14517247 RGD
enables protein serine/threonine kinase activity IMP
IMP: Inferred from mutant phenotype
9786855 RGD
Biological Process GO Annotation Evidence References Source
involved in protein autophosphorylation IDA
IDA: Inferred from direct assay
18216281 RGD
involved in protein phosphorylation IMP
IMP: Inferred from mutant phenotype
9786855 RGD
involved in regulation of actin cytoskeleton organization IMP
IMP: Inferred from mutant phenotype
18216281 RGD
involved in regulation of cytoskeleton organization IDA
IDA: Inferred from direct assay
14517247 RGD
involved in regulation of microtubule cytoskeleton organization IMP
IMP: Inferred from mutant phenotype
18216281 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

serine/threonine-protein kinase TAO1

  • thousand and one amino acid protein 1

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (7)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-112136 TAO Kinase inhibitor 1 99.81% Unkown
HY-181280 VU6083859 Inhibitor 99.75% Unkown
HY-181281 VU6080195 Activator / Unkown
HY-RS14198 TAOK1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-181619 TAO Kinase-IN-3 Inhibitor / Unkown
HY-RS18551 Taok1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS25033 Taok1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Taok1 NCBI NCBI:57551