Pgrmc1 - progesterone receptor membrane component 1 Gene

Also Known as MPR; 25Dx; VEMA; 25-Dx

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 291948

Summary

Predicted to enable heme binding activity and protein homodimerization activity. Involved in several processes, including learning or memory; modification of synaptic structure; and positive regulation of protein localization to plasma membrane. Located in neuron projection; neuronal cell body; and synapse. Orthologous to human PGRMC1 (Progesterone Receptor membrane component 1). [provided by Alliance of Genome Resources, Apr 2022]

Pgrmc1 Products (1)

mRNA Protein Name
NM_021766.2 NP_068534.2 membrane-associated progesterone receptor component 1

Gene Ontology

  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence References Source
involved in associative learning IGI
IGI: Inferred from genetic interaction
25390368 RGD
involved in axon guidance IEP
IEP: Inferred from expression pattern
10656251 RGD
involved in memory IGI
IGI: Inferred from genetic interaction
25390368 RGD
involved in modification of synaptic structure IGI
IGI: Inferred from genetic interaction
25390368 RGD
involved in negative regulation of synapse organization IGI
IGI: Inferred from genetic interaction
25390368 RGD
Cellular Component GO Annotation Evidence References Source
located in cell body IDA
IDA: Inferred from direct assay
25390692 RGD
located in neuron projection IDA
IDA: Inferred from direct assay
25390692 RGD
located in neuronal cell body IDA
IDA: Inferred from direct assay
25390692 RGD
located in synapse IDA
IDA: Inferred from direct assay
25390692 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

membrane-associated progesterone receptor component 1

  • acidic 25 kDa protein

  • membrane-bound progesterone receptor

  • ventral midline antigen

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (8)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-115625 AG-205 99% Unkown
HY-116968 JVW-1009 Antagonist / Unkown
HY-119386 SAS-0132 / Unkown
HY-120008 SAS-1121 Ligand / Unkown
HY-121012 (rac)-AG-205 / Unkown
HY-RS10399 PGRMC1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS20577 Pgrmc1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS27085 Pgrmc1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Pgrmc1 NCBI NCBI:10857