Slc1a5 - solute carrier family 1 member 5 Gene

Also Known as Asct2; Slc1a7; H4-ASCT2

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 292657

Summary

Enables L-aspartate transmembrane transporter activity and L-serine transmembrane transporter activity. Involved in amino acid transport. Predicted to be located in basal plasma membrane. Predicted to be integral component of membrane. Predicted to be active in plasma membrane. Orthologous to human SLC1A5 (solute carrier family 1 member 5). [provided by Alliance of Genome Resources, Apr 2022]

Slc1a5 Products (1)

mRNA Protein Name
NM_175758.3 NP_786934.1 neutral amino acid transporter B(0)

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables L-aspartate transmembrane transporter activity IDA
IDA: Inferred from direct assay
14622120 RGD
enables L-serine transmembrane transporter activity IDA
IDA: Inferred from direct assay
12885409 RGD
enables antiporter activity IDA
IDA: Inferred from direct assay
10698697 RGD
enables ligand-gated channel activity IDA
IDA: Inferred from direct assay
10698697 RGD
Biological Process GO Annotation Evidence References Source
involved in L-aspartate import across plasma membrane IDA
IDA: Inferred from direct assay
14622120 RGD
involved in L-glutamine import across plasma membrane IDA
IDA: Inferred from direct assay
10537079 RGD
involved in L-serine transport IDA
IDA: Inferred from direct assay
12885409 RGD
involved in glutamine secretion IDA
IDA: Inferred from direct assay
10537079 RGD
involved in neutral amino acid transport IDA
IDA: Inferred from direct assay
10698697 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

neutral amino acid transporter B(0)

  • CAZ-associated structural protein

  • H4-system ASC-like transporter

  • sodium-dependent neutral amino acid transporter ASCT2

  • solute carrier family 1 (neutral amino acid transporter), member 5

  • solute carrier family 1, member 7

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (11)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-112683 V-9302 Antagonist 99.46% Unkown
HY-112683A V-9302 hydrochloride Antagonist 99.10% Unkown
HY-179557 iMQT_020 99.45% Unkown
HY-34611 Boc-L-2,4-Diaminobutyric acid Ligand 98.0% Unkown
HY-RS13056 SLC1A5 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-78162 cis-3-Hydroxyproline Substrate 95.0% Unkown
HY-158161 JN-170 Inhibitor / Unkown
HY-N0390G L-Glutamine (GMP) Inhibitor / Unkown
HY-P11756 P-LPK Ligand / Unkown
HY-RS16831 Slc1a5 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS23273 Slc1a5 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Slc1a5 NCBI NCBI:6510