Lbp - lipopolysaccharide binding protein Gene

Also Known as Bpifd2

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 29469

About Lbp

Primary_assembly 3: 146,954,015-146,981,586 forward strand.mRatBN7.2:CM026976.1

This gene has 2 transcripts (splice variants), 104 orthologues, 12 paralogues and is associated with 18 phenotypes. Biased expression in Liver (RPKM 34.4), Heart (RPKM 58.6) and 5 other tissues.

Summary

Enables lipopolysaccharide binding activity. Involved in several processes, including liver development; positive regulation of macrophage activation; and positive regulation of phagocytosis, engulfment. Located in extracellular space. Used to study obesity. Biomarker of liver cirrhosis; obstructive jaundice; and periodontitis. Orthologous to human LBP (lipopolysaccharide binding protein). [provided by Alliance of Genome Resources, Apr 2022]

Lbp Products (1)

mRNA Protein Name
NM_017208.2 NP_058904.2 lipopolysaccharide-binding protein precursor

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables lipopolysaccharide binding IDA
IDA: Inferred from direct assay
22580761 RGD
Biological Process GO Annotation Evidence References Source
involved in liver development IEP
IEP: Inferred from expression pattern
20978830 RGD
involved in positive regulation of macrophage activation IDA
IDA: Inferred from direct assay
10733550 RGD
involved in positive regulation of phagocytosis, engulfment IDA
IDA: Inferred from direct assay
11104656 RGD
involved in regulation of membrane permeability IMP
IMP: Inferred from mutant phenotype
17446308 RGD
involved in response to ethanol IEP
IEP: Inferred from expression pattern
23277536 RGD
Cellular Component GO Annotation Evidence References Source
located in extracellular space IDA
IDA: Inferred from direct assay
22580761 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Lbp Protein Structure

BPI1

BPI1: cd00025 (30 - 251)

LBP_BPI_CETP_C

LBP_BPI_CETP_C: pfam02886 (240 - 477)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 481 a.a.
Protein Preferred Names Protein Names

lipopolysaccharide-binding protein

  • BPI fold containing family D, member 2

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (16)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-141882 DC-LC3in-D5 Inhibitor 98.62% Unkown
HY-172476 DSPE-PEG2000-YIGSR 95.0% Unkown
HY-106010 LBP1 Agonist / Unkown
HY-155437 NEt-iFQ Agonist / Unkown
HY-172475 DSPE-PEG1000-YIGSR / Unkown
HY-172476A DSPE-PEG3400-YIGSR / Unkown
HY-172477 DSPE-PEG5000-YIGSR / Unkown
HY-P11772 LBP-14 / Unkown
HY-P11772A LBP-14-NH2 TFA Inhibitor 98.61% Unkown
HY-RS04226 EHHADH Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS07543 LBP Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS07544 Lbp Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS12272 RPSA Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS16804 Lbp Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS18562 Ehhadh Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS25044 Ehhadh Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Lbp NCBI NCBI:3929