1. Gene
  2. Lbp - lipopolysaccharide binding protein Gene

Lbp - lipopolysaccharide binding protein Gene

Rattus norvegicus

Also known as Bpifd2

Gene ID: 29469 | Gene type: protein coding

About Lbp

Primary_assembly 3: 146,954,015-146,981,586 forward strand.mRatBN7.2:CM026976.1

This gene has 2 transcripts (splice variants), 104 orthologues, 12 paralogues and is associated with 18 phenotypes. Biased expression in Liver (RPKM 34.4), Heart (RPKM 58.6) and 5 other tissues.

Summary

Enables lipopolysaccharide binding activity. Involved in several processes, including liver development; positive regulation of macrophage activation; and positive regulation of phagocytosis, engulfment. Located in extracellular space. Used to study obesity. Biomarker of liver cirrhosis; obstructive jaundice; and periodontitis. Orthologous to human LBP (lipopolysaccharide binding protein). [provided by Alliance of Genome Resources, Apr 2022]

Lbp Products(1)

mRNA Protein Name
NM_017208.2 NP_058904.2 lipopolysaccharide-binding protein precursor

Lbp Protein Structure

BPI1

BPI1: cd00025 (30 - 251)

LBP_BPI_CETP_C

LBP_BPI_CETP_C: pfam02886 (240 - 477)

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  • 481 a.a.
Protein Preferred Names Protein Names

lipopolysaccharide-binding protein

BPI fold containing family D, member 2

Orthologs Information

Species Symbol Source ID
Homo sapiens Lbp NCBI NCBI:3929
Macaca fascicularis Lbp NCBI
Mus musculus Lbp NCBI
Macaca mulatta Lbp NCBI