Mgat3 - beta-1,4-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase Gene

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 29582

Summary

Predicted to enable beta-1,4-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity. Predicted to be involved in N-acetylglucosamine metabolic process; protein localization; and regulation of cell migration. Predicted to act upstream of or within several processes, including amyloid-beta metabolic process; negative regulation of lysosomal protein catabolic process; and positive regulation of protein localization to early endosome. Predicted to be located in Golgi membrane. Predicted to be integral component of membrane. Orthologous to human MGAT3 (beta-1,4-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase). [provided by Alliance of Genome Resources, Apr 2022]

Mgat3 Products (1)

mRNA Protein Name
NM_019239.2 NP_062112.2 beta-1,4-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase
Protein Preferred Names Protein Names

beta-1,4-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase

  • GNT-III

  • N-acetylglucosaminyltransferase III

  • N-glycosyl-oligosaccharide-glycoprotein N-acetylglucosaminyltransferase III

  • glcNAc-T III

  • mannoside acetyl glucosaminyltransferase 3

  • mannosyl (beta-1,4-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase

Related Agents

  • Clinical Phase
  • Pre-clinical Phase

Clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Phase
HY-138942 PF-06427878 Inhibitor / Phase 1

Pre-clinical Phase

Bioactive Molecules (9)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-32219 T863 Inhibitor 99.83% Unkown
HY-103504 (S)-SNAP5114 Inhibitor 98.09% Unkown
HY-108339 PF-06471553 Inhibitor 98.29% Unkown
HY-146280 mGAT3/4-IN-1 Inhibitor / Unkown
HY-146281 mGAT3/4-IN-2 Inhibitor / Unkown
HY-146282 mGAT-IN-1 Inhibitor / Unkown
HY-RS08403 MGAT3 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS20988 Mgat3 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS27505 Mgat3 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Mgat3 NCBI NCBI:4248