mGAT3/4-IN-1
mGAT3/4-IN-1 (compound 19b) is a potent mGAT3/mGAT4 inhibitor, with pIC50 values of 5.31 and 5.24, respectively. mGAT3/4-IN-1 exhibits a significant tactile allodynia reduction in diabetic neuropathic mice.
For research use only. We do not sell to patients.
- CAS No.: 2556833-57-7
- Formula: C26H31ClN2O2S2
- Molecular Weight:503.12
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
pIC50: 4.86 ± 0.10 (mGAT1), 4.98 ± 0.05 (mGAT2), 5.31 ± 0.04 (mGAT3), 5.24 ± 0.05 (mGAT4)[1]
Chemical Information
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CAS No. 2556833-57-7
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Molecular Weight 503.12
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Formula C26H31ClN2O2S2
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SMILES
O=C(C(CCO)N(CC/C=C(C1=C(C)C=CS1)\C2=C(C)C=CS2)C)NCC3=C(Cl)C=CC=C3
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)