Impdh2 - inosine monophosphate dehydrogenase 2 Gene

Also Known as IMPD 2; IMPDH 2

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 301005

Summary

Enables IMP dehydrogenase activity and identical protein binding activity. Involved in purine nucleotide biosynthetic process and retina development in camera-type eye. Predicted to be located in cytosol and nucleus. Predicted to be active in cytoplasm. Orthologous to human IMPDH2 (inosine monophosphate dehydrogenase 2). [provided by Alliance of Genome Resources, Apr 2022]

Impdh2 Products (1)

mRNA Protein Name
NM_199099.3 NP_954530.2 inosine-5'-monophosphate dehydrogenase 2

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables IMP dehydrogenase activity IDA
IDA: Inferred from direct assay
2897864 RGD
enables identical protein binding IPI
IPI: Inferred from physical interaction
2897864 RGD
Biological Process GO Annotation Evidence References Source
involved in retina development in camera-type eye IEP
IEP: Inferred from expression pattern
18295529 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

inosine-5'-monophosphate dehydrogenase 2

  • IMP (inosine 5'-monophosphate) dehydrogenase 2

  • IMP (inosine monophosphate) dehydrogenase 2

  • IMP dehydrogenase 2

  • inosine 5'-phosphate dehydrogenase 2

  • inosine 5-monophosphate dehydrogenase 2

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-147342 β-Benzamide adenine dinucleotide Inhibitor / Unkown
HY-118917 VX-148 Inhibitor / Unkown
HY-174221 IMPDH II/HDAC1-IN-1 Inhibitor / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Impdh2 NCBI NCBI:3615