Cul3 - cullin 3 Gene

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 301555

Summary

Predicted to enable several functions, including Notch binding activity; POZ domain binding activity; and cyclin binding activity. Predicted to be involved in several processes, including COPII vesicle coating; positive regulation of cell cycle process; and protein ubiquitination. Predicted to act upstream of or within several processes, including anaphase-promoting complex-dependent catabolic process; embryonic morphogenesis; and fibroblast apoptotic process. Predicted to be located in several cellular components, including Golgi apparatus; microtubule cytoskeleton; and sperm flagellum. Predicted to be part of Cul3-RING ubiquitin Ligase complex. Human ortholog(s) of this gene implicated in pseudohypoaldosteronism. Orthologous to human CUL3 (cullin 3). [provided by Alliance of Genome Resources, Apr 2022]

Cul3 Products (1)

mRNA Protein Name
NM_001106923.2 NP_001100393.2 cullin-3

Gene Ontology

  • Molecular Function
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
17062563 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

cullin-3

Related Agents

  • Clinical Phase
  • Pre-clinical Phase

Clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Phase
HY-159641 VVD-130037 Activator 99.91% Phase 1

Pre-clinical Phase

Bioactive Molecules (7)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-126075A WS-383 Inhibitor 99.43% Unkown
HY-169766 VVD 065 Degrader 99.71% Unkown
HY-124834 Nrf2 activator-10 98.65% Unkown
HY-RS03361 CUL3 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-126075 WS-383 free base Inhibitor / Unkown
HY-RS18472 Cul3 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS24953 Cul3 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Cul3 NCBI NCBI:8452