2. Gene
  3. Kat2a - lysine acetyltransferase 2A Gene

Kat2a - lysine acetyltransferase 2A Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus

Also known as Gcn5; Gcn5l2

Gene ID: 303539 | Gene type: protein coding

About Kat2a

Primary_assembly 10: 85,632,216-85,640,166 reverse strand.mRatBN7.2:CM026983.1

This gene has 1 transcript (splice variant), 209 orthologues, 11 paralogues and is associated with 4 phenotypes. Biased expression in Brain (RPKM 66.2), Adrenal (RPKM 57.9) and 9 other tissues.

Summary

Enables chromatin binding activity and protein Phosphatase binding activity. Involved in several processes, including alpha-tubulin acetylation; intracellular distribution of mitochondria; and positive regulation of cardiac muscle cell differentiation. Located in chromatin and nucleus. Orthologous to human KAT2A (lysine acetyltransferase 2A). [provided by Alliance of Genome Resources, Apr 2022]

Kat2a Products(1)

mRNA Protein Name
NM_001107050.1 NP_001100520.1 histone acetyltransferase KAT2A

Kat2a Protein Structure

PCAF_N

PCAF_N: pfam06466 (80 - 329)

COG5076

COG5076: cl34891 (487 - 827)

Bromo_gcn5_like

Bromo_gcn5_like: cd05509 (727 - 826)

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  • 833 a.a.
Protein Preferred Names Protein Names

histone acetyltransferase KAT2A

GCN5 general control of amino acid synthesis-like 2

K(lysine) acetyltransferase 2A

general control of amino acid synthesis 5-like 2

Related Agents

Pre-clinical Phase
Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS07074 KAT2A Human Pre-designed siRNA Set A / Unkown
HY-RS07075 Kat2a Mouse Pre-designed siRNA Set A / Unkown
HY-RS07076 Kat2a Rat Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Kat2a NCBI NCBI:2648