Cd34 - CD34 molecule Gene

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 305081

Summary

Predicted to enable carbohydrate binding activity and sulfate binding activity. Involved in glomerular filtration and mesangial cell-matrix adhesion. Located in apical plasma membrane; basal plasma membrane; and lysosome. Part of glomerular endothelium fenestra. Biomarker of diabetic retinopathy. Orthologous to human CD34 (CD34 molecule). [provided by Alliance of Genome Resources, Apr 2022]

Cd34 Products (2)

mRNA Protein Name
NM_001107202.3 NP_001100672.1 hematopoietic progenitor cell antigen CD34 isoform 1 precursor
NM_001412747.1 NP_001399676.1 hematopoietic progenitor cell antigen CD34 isoform 2 precursor

Gene Ontology

  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence References Source
involved in glomerular filtration IEP
IEP: Inferred from expression pattern
18319274 RGD
involved in mesangial cell-matrix adhesion IEP
IEP: Inferred from expression pattern
18319274 RGD
Cellular Component GO Annotation Evidence References Source
located in apical plasma membrane IDA
IDA: Inferred from direct assay
18319274 RGD
located in basal plasma membrane IDA
IDA: Inferred from direct assay
18319274 RGD
part of glomerular endothelium fenestra IDA
IDA: Inferred from direct assay
18319274 RGD
located in lysosome IDA
IDA: Inferred from direct assay
18319274 RGD
located in plasma membrane IDA
IDA: Inferred from direct assay
18319274 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

hematopoietic progenitor cell antigen CD34

  • CD34 antigen

Recombinant Cd34 Proteins

Cat. No. Product Name Accession Purity
HY-P74304 CD34 Protein, Rat (HEK293, Fc) B1PLB1 (E37-T291) ≥ 95%, as determined by reducing SDS-PAGE.

Related Agents

  • Approval
  • Clinical Phase
  • Pre-clinical Phase

Approval

Bioactive Molecules (2)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-15306 Eltrombopag 99.94% Yes
HY-15306A Eltrombopag Olamine 99.96% Yes

Clinical Phase

Bioactive Molecules (2)
Cat. No. Product Name Effect
Purity Phase
HY-19867A Burixafor hydrobromide Antagonist 99.70% Phase 2
HY-19867 Burixafor Antagonist / Phase 2
Inhibitory Antibodies (3)
Cat. No. Product Name Effect
Purity Phase
HY-P990351 Anti-CD34 Antibody Inhibitor 99.90% Phase 4
HY-P991329 ASP-1948 Inhibitor / Phase 1
HY-P991419 MSB-0254 Inhibitor / Phase 1

Pre-clinical Phase

Bioactive Molecules (13)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-NP199 Bovine pituitary extract Modulator / Unkown
HY-170823 PRC1-IN-1 Inhibitor 97.30% Unkown
HY-150109A Purinostat Inhibitor 98.04% Unkown
HY-106784 Ajoene ≥99.0% Unkown
HY-110208 BRD9876 99.37% Unkown
HY-124693 DB1055 Inducer 99.68% Unkown
HY-108417 Debio 0617B Inhibitor / Unkown
HY-125090 PHA-680626 / Unkown
HY-15001A Stemregenin 1 hydrochloride Antagonist / Unkown
HY-150239 BAY-364 Inhibitor / Unkown
HY-RS02236 CD34 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS16784 Cd34 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS23224 Cd34 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
Inhibitory Antibodies (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-P990352 Anti-CD36 Antibody Inhibitor 99.43% Unkown
HY-P990274 Anti-Canine CD34 Antibody (1H6) / Unkown
HY-P991328 MAb604.107 Inhibitor / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Cd34 NCBI NCBI:947