Cdk13 - cyclin-dependent kinase 13 Gene
Also Known as Cdc2l5
Species: Rattus norvegicus
About Cdk13
This gene has 2 transcripts (splice variants), 207 orthologues, 24 paralogues and is associated with 9 phenotypes. Biased expression in Thymus (RPKM 25.), Spleen (RPKM 226.6) and 9 other tissues.
Summary
Predicted to enable cyclin binding activity; protein kinase binding activity; and protein serine/threonine kinase activity. Predicted to be involved in RNA metabolic process; hemopoiesis; and regulation of transcription by RNA polymerase II. Predicted to act upstream of or within negative regulation of stem cell differentiation. Predicted to be located in Golgi apparatus; cytosol; and nuclear speck. Predicted to be part of cyclin K-CDK13 complex and cyclin/CDK positive transcription elongation factor complex. Predicted to be active in nucleus. Human ortholog(s) of this gene implicated in congenital heart defects, dysmorphic facial features, and intellectual developmental disorder. Orthologous to human CDK13 (cyclin dependent kinase 13). [provided by Alliance of Genome Resources, Apr 2022]
Cdk13 Products (4)
| mRNA | Protein | Name |
|---|---|---|
| NM_001271295.2 | NP_001258224.2 | cyclin-dependent kinase 13 isoform 1 |
| NM_001271296.2 | NP_001258225.2 | cyclin-dependent kinase 13 isoform 2 |
| NM_001271295.2 | NP_001258224.2 | cyclin-dependent kinase 13 isoform 1 |
| NM_001271296.2 | NP_001258225.2 | cyclin-dependent kinase 13 isoform 2 |
Cdk13 Protein Structure
STKc_CDK12: cd07864 (696 - 997)
- 0
- 300
- 600
- 900
- 1200
- 1527 a.a.
| Protein Preferred Names | Protein Names | |
|---|---|---|
|
cyclin-dependent kinase 13 |
|