2. Gene
  3. ACAT2 - acetyl-CoA acetyltransferase 2 Gene

ACAT2 - acetyl-CoA acetyltransferase 2 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus

Also known as Acat3; Ab2-076

Gene ID: 308100 | Gene type: protein coding

About ACAT2

Primary_assembly 1: 47,695,788-47,752,821 forward strand.mRatBN7.2:CM026974.1

This gene has 5 transcripts (splice variants), 213 orthologues, 7 paralogues and is associated with 7 phenotypes. Biased expression in Liver (RPKM 12.4), Brain (RPKM 14.9) and 9 other tissues.

Summary

Enables acetyl-CoA C-acetyltransferase activity. Involved in several processes, including bile acid signaling pathway; ketone body catabolic process; and liver development. Located in cytosol. Biomarker of premature menopause. Human ortholog(s) of this gene implicated in coronary artery disease. Orthologous to human ACAT2 (acetyl-CoA acetyltransferase 2). [provided by Alliance of Genome Resources, Apr 2022]

ACAT2 Products(1)

mRNA Protein Name
NM_001006995.1 NP_001006996.1 acetyl-CoA acetyltransferase, cytosolic

ACAT2 Protein Structure

PRK05790

PRK05790: PRK05790 (7 - 395)

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  • 100
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  • 397 a.a.
Protein Preferred Names Protein Names

acetyl-CoA acetyltransferase, cytosolic

acetyl-Coenzyme A acetyltransferase 2

acetyl-Coenzyme A acetyltransferase 3

cytosolic acetoacetyl-CoA thiolase

Recombinant ACAT2 Proteins

Cat. No. Product Name Accession Purity
HY-P75543 ACAT2 Protein, Rat (His) Q5XI22 (M1-G397) ≥95%

Related Agents

Clinical Phase
Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Phase
HY-13215 Avasimibe Inhibitor 99.50% Phase 3
HY-100401A Pactimibe sulfate Inhibitor 98.22% Phase 3
HY-100400A K-604 dihydrochloride Inhibitor ≥99.0% Phase 2

Orthologs Information

Species Symbol Source ID
Homo sapiens ACAT2 NCBI NCBI:39