2. Disease Areas
  3. Urogenital Disease
  4. Female Reproductive System Disease
  5. Menopause

Menopause

Menopause is the permanent cessation of menstruation resulting from the depletion of ovarian follicles, leading to a decline in estrogen and progesterone production.

References:

Menopause (3):

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-181682
    NK3R antagonist-1
    NK3R antagonist-1 is an orally active neurokinin-3 receptor (NK3R) antagonist with an IC50 of 53.61 nM. NK3R antagonist-1 reduces plasma luteinizing hormone (LH) levels in ovariectomized rat models. NK3R antagonist-1 is applicable to research related to menopausal hot flushes.
    NK3R antagonist-1
  • HY-B0141E
    ent-Estradiol 3736-22-9
    Ent-Estradiol is the enantiomer of Estradiol (HY-B0141). Ent-Estradiol is a highly selective estrogen receptor ligand, but does not possess estrogenic activity. Ent-Estradiol displays IC50 values of 24.9 nM, 9.59 nM and 8.17 nM for human, rat and mouse ERβ, and 151 nM, 246 nM and 268 nM for human, rat and mouse ERα, respectively. Ent-Estradiol can be used for the study of menopausal physiological changes.
    ent-Estradiol
  • HY-B0709
    Estradiol acetate 4245-41-4
    Estradiol acetate is a novel orally active Estradiol (HY-B0141) prodrug. Estradiol acetate reduces the frequency and severity of postmenopause symptoms. Estradiol acetate can be used in the research of menopausal symptoms.
    Estradiol acetate