Estradiol acetate
Estradiol acetate is a novel orally active Estradiol (HY-B0141) prodrug. Estradiol acetate reduces the frequency and severity of postmenopause symptoms. Estradiol acetate can be used in the research of menopausal symptoms.
For research use only. We do not sell to patients.
- CAS No.: 4245-41-4
- Formula: C20H26O3
- Molecular Weight:314.42
-
Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Biological Activity
-
Chemical Information
- Purity & Documentation
- References
-
Help & FAQs
Biological Activity
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| CHO | Inhibition |
101.033 %
Compound: ESTRADIOL ACETATE
|
Inhibition of sodium fluorescein uptake in OATP1B3-transfected CHO cells at an equimolar substrate-inhibitor concentration of 10 uM
Inhibition of sodium fluorescein uptake in OATP1B3-transfected CHO cells at an equimolar substrate-inhibitor concentration of 10 uM
|
[PMID: 23571415] |
| CHO | Inhibition |
456.299 %
Compound: ESTRADIOL ACETATE
|
Inhibition of sodium fluorescein uptake in OATP1B1-transfected CHO cells at an equimolar substrate-inhibitor concentration of 10 uM
Inhibition of sodium fluorescein uptake in OATP1B1-transfected CHO cells at an equimolar substrate-inhibitor concentration of 10 uM
|
[PMID: 23571415] |
| NCT Number | Sponsor | Condition | Start Date |
Phase
|
|---|---|---|---|---|
| NCT01329991 | Plexxikon| | 2011-05 | PHASE1 |
Chemical Information
-
CAS No. 4245-41-4
-
Molecular Weight 314.42
-
Formula C20H26O3
-
SMILES
C[C@@]12[C@](CC[C@@H]2O)([H])[C@@]3([H])[C@@](CC1)([H])C4=CC=C(OC(C)=O)C=C4CC3
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Utian WH, et al. Comparative controlled trial of a novel oral estrogen therapy, estradiol acetate, for relief of menopause symptoms. Menopause. 2005 Nov-Dec;12(6):708-15. [Content Brief]
[2]. Speroff L, et al. Efficacy of a new, oral estradiol acetate formulation for relief of menopause symptoms. Menopause. 2006 May-Jun;13(3):442-50. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Estradiol acetate Related Classifications
HY-B0709 Related Classifications
Powered by Bioz