Usp25 - ubiquitin specific peptidase 25 Gene

Species: Mus musculus

Gene Type: protein coding
Gene ID: 30940

Summary

Predicted to enable SUMO binding activity; cysteine-type peptidase activity; and enzyme binding activity. Involved in several processes, including interleukin-17-mediated signaling pathway; intracellular signal transduction; and mRNA metabolic process. Predicted to be located in endoplasmic reticulum. Predicted to be part of Proteasome complex. Predicted to be active in cytosol and nucleus. Is expressed in several structures, including alimentary system; genitourinary system; musculature; nervous system; and sensory organ. Orthologous to human USP25 (ubiquitin specific peptidase 25). [provided by Alliance of Genome Resources, Apr 2022]

Usp25 Products (1)

mRNA Protein Name
NM_013918.2 NP_038946.2 ubiquitin carboxyl-terminal hydrolase 25

Gene Ontology

  • Biological Process
Biological Process GO Annotation Evidence References Source
involved in I-kappaB phosphorylation IMP
IMP: Inferred from mutant phenotype
23042150 MGI
involved in chemokine production IMP
IMP: Inferred from mutant phenotype
23042150 MGI
involved in cytokine production IMP
IMP: Inferred from mutant phenotype
23042150 MGI
involved in immune response IMP
IMP: Inferred from mutant phenotype
23042150 MGI
involved in interleukin-17-mediated signaling pathway IDA
IDA: Inferred from direct assay
23042150 MGI
involved in interleukin-17-mediated signaling pathway IMP
IMP: Inferred from mutant phenotype
23042150 MGI
involved in mRNA metabolic process IMP
IMP: Inferred from mutant phenotype
23042150 MGI
involved in response to oxidative stress IMP
IMP: Inferred from mutant phenotype
23453926 MGI
involved in stress-activated protein kinase signaling cascade IMP
IMP: Inferred from mutant phenotype
23042150 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

ubiquitin carboxyl-terminal hydrolase 25

  • deubiquitinating enzyme 25

  • mUSP25

  • ubiquitin specific protease 25

  • ubiquitin thioesterase 25

  • ubiquitin thiolesterase 25

  • ubiquitin-specific-processing protease 25

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-184244 CAS-010 Inhibitor / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Usp25 NCBI NCBI:29761