Mttp - microsomal triglyceride transfer protein Gene

Rattus norvegicus

Also known as MTP

Gene ID: 310900 | Gene type: protein coding

About Mttp

Primary_assembly 2: 226,613,090-226,654,239 reverse strand.mRatBN7.2:CM026975.1

This gene has 1 transcript (splice variant), 210 orthologues and is associated with 11 phenotypes.

Summary

Enables apolipoprotein binding activity and lipid transfer activity. Involved in several processes, including Cholesterol homeostasis; lipoprotein metabolic process; and response to calcium ion. Located in several cellular components, including basolateral plasma membrane; cell projection membrane; and rough endoplasmic reticulum. Biomarker of familial hyperlipidemia. Human ortholog(s) of this gene implicated in several diseases, including abdominal obesity-metabolic syndrome 1; abetalipoproteinemia; familial hypercholesterolemia; hyperinsulinism; and obesity. Orthologous to human MTTP (microsomal triglyceride transfer protein). [provided by Alliance of Genome Resources, Apr 2022]

Mttp Products(1)

mRNA	Protein	Name
NM_001107727.1	NP_001101197.1	microsomal triglyceride transfer protein large subunit precursor

Related Agents

Pre-clinical Phase

Bioactive Molecules (3)

Cat. No.	Product Name	Purity	Rare Diseases
HY-RS08822	MTTP Human Pre-designed siRNA Set A	/	Unkown
HY-RS08823	Mttp Mouse Pre-designed siRNA Set A	/	Unkown
HY-RS08824	Mttp Rat Pre-designed siRNA Set A	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Mttp	NCBI	NCBI:4547

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