Pak5 - p21 (RAC1) activated kinase 5 Gene
Also Known as Pak7; PAK-5; PAK-7
Species: Rattus norvegicus
About Pak5
This gene has 1 transcript (splice variant), 214 orthologues, 36 paralogues and is associated with 3 phenotypes. Restricted expression toward (RPKM 12.5).
Summary
Predicted to enable protein serine/threonine kinase activity. Predicted to be involved in intracellular signal transduction; protein phosphorylation; and regulation of MAPK cascade. Predicted to act upstream of or within learning or memory; locomotory behavior; and negative regulation of extrinsic apoptotic signaling pathway. Predicted to be located in mitochondrion and nucleoplasm. Predicted to be active in cytoplasm and synapse. Orthologous to human PAK5 (p21 (RAC1) activated kinase 5). [provided by Alliance of Genome Resources, Apr 2022]
Pak5 Products (1)
| mRNA | Protein | Name |
|---|---|---|
| NM_001107781.1 | NP_001101251.1 | serine/threonine-protein kinase PAK 5 |
Pak5 Protein Structure
CRIB_PAK_like: cd01093 (8 - 54)
STKc_PAK5: cd06658 (424 - 715)
- 0
- 200
- 400
- 600
- 718 a.a.
| Protein Preferred Names | Protein Names | |
|---|---|---|
|
serine/threonine-protein kinase PAK 5 |
|
|
Related Agents
- Clinical Phase
- Pre-clinical Phase
Clinical Phase
| Cat. No. | Product Name |
Effect
|
Purity |
Phase
|
|---|---|---|---|---|
| HY-13007 | PF-3758309 | Inhibitor | 99.79% | Phase 1 |
Pre-clinical Phase
| Cat. No. | Product Name |
Effect
|
Purity |
Rare Diseases
|
|---|---|---|---|---|
| HY-15323 | PRT062607 Hydrochloride | Inhibitor | 98.07% | Unkown |
| HY-15324 | PRT062607 acetate | Inhibitor | 99.83% | Unkown |
| HY-13007B | PF-3758309 dihydrochloride | Inhibitor | / | Unkown |
| HY-13007A | PF-3758309 hydrochloride | Inhibitor | / | Unkown |
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