Grk3 - G protein-coupled receptor kinase 3 Gene

Also Known as Adrbk2; Bark-2; Adrbk-2; 4833444A01Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 320129

Summary

Enables G protein-coupled receptor kinase activity. Predicted to be involved in several processes, including cellular protein metabolic process; desensitization of G protein-coupled receptor signaling pathway; and inositol phosphate metabolic process. Predicted to act upstream of or within phosphorylation. Predicted to be located in several cellular components, including Z disc; dendrite; and sperm midpiece. Is expressed in adrenal gland; alimentary system; nervous system; retina; and vibrissa. Orthologous to human GRK3 (G protein-coupled receptor kinase 3). [provided by Alliance of Genome Resources, Apr 2022]

Grk3 Products (2)

mRNA Protein Name
NM_001285806.1 NP_001272735.1 beta-adrenergic receptor kinase 2 isoform 3
NM_177078.4 NP_796052.2 beta-adrenergic receptor kinase 2 isoform 1

Gene Ontology

  • Molecular Function
Molecular Function GO Annotation Evidence References Source
enables G protein-coupled receptor kinase activity IDA
IDA: Inferred from direct assay
1869533 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

beta-adrenergic receptor kinase 2

  • adrenergic receptor kinase, beta 2

  • beta ARK2

  • beta-ARK-2

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (4)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-103045A CMPD101 hydrochloride Inhibitor / Unkown
HY-RS05814 GRK3 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS20749 Grk3 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS27261 Grk3 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Grk3 NCBI NCBI:157