HOXA6 - homeobox A6 Gene

Also Known as HOX1; HOX1B; HOX1.2

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 3203

About HOXA6

Cytogenetic location: 7p15.2 Genomic coordinates (GRCh38): 7:27,145,396-27,147,774 (from NCBI)

This gene has 2 transcripts (splice variants), 118 orthologues and 42 paralogues. Biased expression in endometrium (RPKM 5.2), kidney (RPKM 2.8) and 10 other tissues.

Summary

In vertebrates, the genes encoding the class of transcription factors called homeobox genes are found in clusters named A, B, C, and D on four separate chromosomes. Expression of these proteins is spatially and temporally regulated during embryonic development. This gene is part of the A cluster on chromosome 7 and encodes a DNA-binding transcription factor which may regulate gene expression, morphogenesis, and differentiation. [provided by RefSeq, Jul 2008]

HOXA6 Products (1)

mRNA Protein Name
NM_024014.4 NP_076919.1 homeobox protein Hox-A6

Gene Ontology

  • Molecular Function
Molecular Function GO Annotation Evidence References Source
enables sequence-specific double-stranded DNA binding IDA
IDA: Inferred from direct assay
28473536 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

HOXA6 Protein Structure

Homeobox

Homeobox: Homeobox domain (156 - 212)

  • 0
  • 100
  • 200
  • 233 a.a.
Protein Preferred Names Protein Names

homeobox protein Hox-A6

  • homeo box 1B

Related Diseases

Diseases Alias
Angiomatous Meningioma
Parasagittal Meningioma
Cerebral Convexity Meningioma

  • Cerebral Hemispheric Convexity Meningioma
Foster-Kennedy Syndrome

  • Disorder Of The Optic Nerve

  • Optic Nerve Diseases

  • Disease Of Optic Cranial Nerve

  • Disease Of Optic Nerve

  • Disease Of Second Cranial Nerve

  • Disorder Of Optic Cranial Nerve

  • Disorder Of Second Cranial Nerve

  • Disorders Of 2nd Nerve
Clear Cell Meningioma
Anterior Cranial Fossa Meningioma

  • Meningioma Of The Anterior Fossa
Cerebral Falx Meningioma

  • Falcine Meningioma

  • Falx Cerebri Meningioma
Choroid Plexus Meningioma

  • Choroid Meningioma

  • Meningioma Of The Choroid Plexus
Brain Meningioma

  • Intracranial Meningioma
Cerebral Meningioma

  • Meningioma Of Cerebrum
Meningioma, Familial

  • Meningioma

  • Familial Meningioma

  • Meningioma, Familial, Susceptibility To

  • Meningeal Neoplasm

  • Meningeal Neoplasms

  • Meningiomas

  • Meningioma, Nf2-Related, Somatic

  • Meningioma, Sis-Related

  • Meningothelial Cell Tumor

  • Neoplasm Of The Meninges

  • Primary Meningeal Tumor

  • Familial Multiple Meningioma

  • MNGMA

  • Meningioma, Benign, No Icd-O Subtype

  • Intracranial Meningioma

  • Meningothelial Cell Neoplasm

  • Supratentorial Meningioma

  • Primary Neoplasm Of Spinal Meninges

  • Benign Intracranial Meningioma

  • Benign Meningioma

  • Meningeal Tumours

  • Meningeal Sarcoma Of Unspecified Site

  • Meningothelial Sarcoma Of Unspecified Site
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS06301 HOXA6 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Rattus norvegicus HOXA6 RGD RGD:1590236
Canis familiaris HOXA6 VGNC VGNC:49909
Mus musculus HOXA6 MGD MGI:96178
Macaca mulatta HOXA6 VGNC VGNC:108415
Bos taurus HOXA6 VGNC VGNC:29914
Felis catus HOXA6 VGNC VGNC:80598
Others HOXA6 NCBI