Ifnl3 - interferon lambda 3 Gene

Also Known as Il28; IFL-1; Il28b; IL-28B; If1ia2; INF-alpha; INF-lambda

Species: Mus musculus

Gene Type: protein coding
Gene ID: 338374

Summary

Predicted to enable signaling receptor binding activity. Acts upstream of or within innate immune response. Located in extracellular space. Human ortholog(s) of this gene implicated in cryoglobulinemia; hepatitis C; liver cirrhosis; and thrombocytopenia. Orthologous to human IFNL2 (interferon lambda 2) and IFNL3 (interferon lambda 3). [provided by Alliance of Genome Resources, Apr 2022]

Ifnl3 Products (1)

mRNA Protein Name
NM_177396.1 NP_796370.1 interferon lambda-3 precursor

Gene Ontology

  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence References Source
acts upstream of or within innate immune response IDA
IDA: Inferred from direct assay
16751416 MGI
Cellular Component GO Annotation Evidence References Source
located in extracellular space IDA
IDA: Inferred from direct assay
16751416 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

interferon lambda-3

  • IFN-lambda-3

  • interferon 1ia2

  • interferon alpha

  • interleukin 28

  • interleukin-28B

Recombinant Ifnl3 Proteins

Cat. No. Product Name Accession Purity
HY-P74851 IFN-lambda 3/IL-28B Protein, Mouse (HEK293, His) Q8CGK6 (D20-V193) ≥ 95%, as determined by reducing SDS-PAGE.
HY-P700204AF Animal-Free IFN-lambda 3/IL-28B Protein, Mouse (His) Q8CGK6 (D20-V193) ≥ 95%, as determined by reducing SDS-PAGE.

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (4)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS06593 IFNL3 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-174658 Human IFNL3 mRNA / Unkown
HY-RS19446 Ifnl3 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS25938 Ifnl3 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Ifnl3 NCBI NCBI:282617