2. Gene
  3. Cdk14 - cyclin-dependent kinase 14 Gene

Cdk14 - cyclin-dependent kinase 14 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus

Also known as Pftk1

Gene ID: 362316 | Gene type: protein coding

About Cdk14

Primary_assembly 4: 28,666,843-29,258,861 forward strand.mRatBN7.2:CM026977.1

This gene has 3 transcripts (splice variants), 201 orthologues, 24 paralogues and is associated with 2 phenotypes. Biased expression in Brain (RPKM 211.8), Lung (RPKM 2.1) and 9 other tissues.

Summary

Predicted to enable cyclin binding activity and cyclin-dependent protein serine/threonine kinase activity. Predicted to be involved in mitotic cell cycle phase transition; protein phosphorylation; and regulation of canonical Wnt signaling pathway. Predicted to be located in nucleoplasm and plasma membrane. Predicted to be part of cytoplasmic cyclin-dependent protein kinase holoenzyme complex. Predicted to be active in cytosol and nucleus. Orthologous to human CDK14 (cyclin dependent kinase 14). [provided by Alliance of Genome Resources, Apr 2022]

Cdk14 Products(3)

mRNA Protein Name
NM_001395583.1 NP_001382512.1 cyclin-dependent kinase 14 isoform 1
NM_001395582.1 NP_001382511.1 cyclin-dependent kinase 14 isoform 1
NM_001395584.1 NP_001382513.1 cyclin-dependent kinase 14 isoform 2

Cdk14 Protein Structure

STKc_PFTAIRE1

STKc_PFTAIRE1: cd07869 (128 - 430)

  • 0
  • 100
  • 200
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  • 400
  • 469 a.a.
Protein Preferred Names Protein Names

cyclin-dependent kinase 14

PFTAIRE protein kinase 1

cell division protein kinase 14

Related Agents

Pre-clinical Phase
Bioactive Molecules (2)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-127104 FMF-04-159-2 Inhibitor 98.92% Unkown
HY-160213 JA397 Inhibitor / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Cdk14 NCBI NCBI:5218