2. Gene
  3. LAIR2 - leukocyte associated immunoglobulin like receptor 2 Gene

LAIR2 - leukocyte associated immunoglobulin like receptor 2 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Homo sapiens

Also known as CD306

Gene ID: 3904 | Gene type: protein coding

About LAIR2

Cytogenetic location: 19q13.42 Genomic coordinates (GRCh38): 19:54,502,831-54,510,687 (from NCBI)

This gene has 4 transcripts (splice variants), 1 gene allele, 215 orthologues and 25 paralogues. Biased expression in placenta (RPKM 4.7), lymph node (RPKM 0.9) and 3 other tissues.

Summary

The protein encoded by this gene is a member of the immunoglobulin superfamily. It was identified by its similarity to leukocyte-associated immunoglobulin-like receptor 1, a membrane-bound receptor that modulates innate immune response. The protein encoded by this locus is a soluble receptor that may play roles in both inhibition of collagen-induced platelet aggregation and vessel formation during placental implantation. This gene maps to a region of 19q13.4, termed the leukocyte receptor cluster, which contains 29 genes in the immunoglobulin superfamily. Alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, Sep 2013]

LAIR2 Products(2)

mRNA Protein Name
NM_002288.6 NP_002279.2 leukocyte-associated immunoglobulin-like receptor 2 isoform a precursor
NM_021270.5 NP_067154.1 leukocyte-associated immunoglobulin-like receptor 2 isoform b precursor

LAIR2 Protein Structure

Ig_2

Ig_2: Immunoglobulin domain (29 - 120)

  • 0
  • 100
  • 152 a.a.
Protein Preferred Names Protein Names

leukocyte-associated immunoglobulin-like receptor 2

LAIR-2

Recombinant LAIR2 Proteins

Cat. No. Product Name Accession Purity
HY-P72391 LAIR2 Protein, Human (Biotinylated, HEK293, Avi-His) Q6ISS4 (Q22-P152) ≥95%
HY-P72527 LAIR2 Protein, Human (HEK293, His) Q6ISS4 (Q22-P152) ≥95%
HY-P77050 LAIR2 Protein, Human (HEK293) Q6ISS4/NP_002279.2 (Q22-P152) ≥95%
HY-P77051 LAIR2 Protein, Human (152a.a, HEK293, His) Q6ISS4 (M1-P152) ≥95%
HY-P77052 LAIR2 Protein, Human (HEK293, Low Endotoxin) Q6ISS4 (M1-P152) ≥95%
HY-P78323 LAIR2 Protein, Human (HEK293, His-Avi) Q6ISS4 (Q22-P152) ≥95%

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS07495 LAIR2 Human Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Mus musculus LAIR2 MGD MGI:105492
Others LAIR2 NCBI