MT1F - metallothionein 1F Gene

Also Known as MT1

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 4494

About MT1F

Cytogenetic location: 16q13 Genomic coordinates (GRCh38): 16:56,657,959-56,659,303 (from NCBI)

This gene has 4 transcripts (splice variants), 216 orthologues and 11 paralogues. Biased expression in thyroid (RPKM 263.0), kidney (RPKM 198.1) and 9 other tissues.

Summary

Predicted to enable zinc ion binding activity. Involved in cellular response to cadmium ion. Located in cytoplasm and nucleus. [provided by Alliance of Genome Resources, Apr 2022]

MT1F Products (2)

mRNA Protein Name
NM_001301272.2 NP_001288201.1 metallothionein-1F isoform 2
NM_005949.4 NP_005940.1 metallothionein-1F isoform 1

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
25416956 GOA
Biological Process GO Annotation Evidence References Source
involved in cellular response to cadmium ion IEP
IEP: Inferred from expression pattern
16827180 GOA
Cellular Component GO Annotation Evidence References Source
located in cytoplasm IDA
IDA: Inferred from direct assay
8619255 GOA
located in nucleus IDA
IDA: Inferred from direct assay
8619255 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

MT1F Protein Structure

Metallothio

Metallothio: Metallothionein (1 - 60)

  • 0
  • 61 a.a.
Protein Preferred Names Protein Names

metallothionein-1F

  • MT-1F

MT1F Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
MT1F P04733 NOP2 Homo sapiens P46087
Y2H Array
25416956
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Diseases

Diseases Alias
Deficiency Anemia

  • Anemia

  • Deficiency Anemias

  • Anaemia
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (2)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS08738 MT1F Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS25638 Mt1f Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Mus musculus MT1F MGD MGI:97171
Others MT1F NCBI