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CD274 - CD274 molecule Gene

Also Known as PDL1; PD-L1

Species: Canis lupus familiaris (sub-species: familiaris)

Gene Type: protein coding

Gene ID: 484186

About CD274

Primary_assembly 1: 94,139,343-94,159,596 forward strand.ROS_Cfam_1.0:CM025100.1

This gene has 2 transcripts (splice variants), 102 orthologues and 7 paralogues.

mRNA	Protein	Name
NM_001291972.1	NP_001278901.1	programmed cell death 1 ligand 1 precursor

Protein Preferred Names	Protein Names
programmed cell death 1 ligand 1	programmed death ligand 1

Cat. No.	Product Name	Accession	Purity
HY-P73717	PD-L1 Protein, Canine (HEK293, Fc)	NP_001278901 (F19-R236)	≥ 95%, as determined by reducing SDS-PAGE.
HY-P78633	PD-L1 Protein, Canine (HEK293, His)	E2RKZ5/NP_001278901.1 (F19-R236)	≥ 90%, as determined by reducing SDS-PAGE.

Inhibitory Antibodies (6)

Cat. No.	Product Name	Effect	Purity	Phase
HY-P99903	Simridarlimab	Inhibitor	99.81%	Phase 2
HY-P990014	Danburstotug	Inhibitor	98.76%	Phase 2
HY-P99698	Lesabelimab	Inhibitor	97.34%	Phase 2
HY-P990623	MDX-1105	Inhibitor	≥99.0%	Phase 1
HY-P991354	GR-1405	Antagonist	/	Phase 1
HY-P991356	FAZ-053	Antagonist	/	Phase 1

Bioactive Molecules (4)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS02217	CD274 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown
HY-RS02218	Cd274 Mouse Pre-designed siRNA Set A	Pre-designed Set	/	Unkown
HY-RS02219	Cd274 Rat Pre-designed siRNA Set A	Pre-designed Set	/	Unkown
HY-14243	CEP-14083	Inhibitor	/	Unkown

Inhibitory Antibodies (6)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-P990899	Amostomig		97.931%	Unkown
HY-P991024	Solabafusp alfa	Inhibitor	97.17%	Unkown
HY-P991151	Opamtistomig	Inhibitor	99.69%	Unkown
HY-P991355	PDL-GEX	Antagonist	/	Unkown
HY-P991357	STT-001	Antagonist	/	Unkown
HY-P992385	IMM25011	Inhibitor	/	Unkown

Species	Symbol	Source	ID
Homo sapiens	CD274	NCBI	NCBI:29126