Nectin4 - nectin cell adhesion molecule 4 Gene

Also Known as Pvrl4; RGD1559826

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 498281

Summary

Predicted to enable identical protein binding activity. Predicted to be involved in heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules and homophilic cell adhesion via plasma membrane adhesion molecules. Predicted to be located in plasma membrane. Predicted to be active in adherens junction. Orthologous to human NECTIN4 (nectin cell adhesion molecule 4). [provided by Alliance of Genome Resources, Apr 2022]

Nectin4 Products (1)

mRNA Protein Name
NM_001109076.1 NP_001102546.1 nectin-4 precursor
Protein Preferred Names Protein Names

nectin-4

  • poliovirus receptor-related 4

  • poliovirus receptor-related protein 4

Related Agents

  • Approval
  • Clinical Phase
  • Pre-clinical Phase

Approval

Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-P99016A Enfortumab vedotin-ejfv Inhibitor 99.69% Unkown
Inhibitory Antibodies (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-P99016 Enfortumab Inhibitor 99.90% Unkown

Clinical Phase

Inhibitory Antibodies (2)
Cat. No. Product Name Effect
Purity Phase
HY-P99016B Enfortumab vedotin-ejfv (solution) Inhibitor 99.78% Phase 3
HY-P990977 Bulumtatug ≥99.0% Phase 1

Pre-clinical Phase

Bioactive Molecules (6)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-147271 Mal-PEG8-Val-Ala-PAB-Exatecan Inhibitor 99.48% Unkown
HY-178489 BGC1614 / Unkown
HY-P11837 NECT-224 / Unkown
HY-RS09177 NECTIN4 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS21247 Nectin4 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS27764 Nectin4 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
Inhibitory Antibodies (4)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-P991707 Notiretatug Inhibitor ≥99.0% Unkown
HY-P991742 LY4101174 Antibody 99.46% Unkown
HY-P992133 Sutantatug Inhibitor 99.9% Unkown
HY-P99016C Enfortumab (powder) Inhibitor / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Nectin4 NCBI NCBI:81607