Preb - prolactin regulatory element binding Gene

Species: Mus musculus

Gene Type: protein coding
Gene ID: 50907

Summary

Enables GTPase binding activity and guanyl-nucleotide exchange factor activity. Predicted to be involved in several processes, including COPII vesicle coating; protein transport; and regulation of COPII vesicle coating. Predicted to act upstream of or within protein transport and vesicle-mediated transport. Predicted to be located in endoplasmic reticulum exit site and nucleus. Predicted to be integral component of endoplasmic reticulum membrane. Is expressed in several structures, including central nervous system; embryo mesenchyme; jaw; metanephros; and surface ectoderm. Orthologous to human PREB (Prolactin regulatory element binding). [provided by Alliance of Genome Resources, Apr 2022]

Preb Products (2)

mRNA Protein Name
NM_001294302.1 NP_001281231.1 prolactin regulatory element-binding protein isoform 2
NM_016703.3 NP_057912.2 prolactin regulatory element-binding protein isoform 1

Gene Ontology

  • Molecular Function
Molecular Function GO Annotation Evidence References Source
enables GTPase binding IPI
IPI: Inferred from physical interaction
11422940 MGI
enables guanyl-nucleotide exchange factor activity IDA
IDA: Inferred from direct assay
11422940 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

prolactin regulatory element-binding protein

  • mammalian guanine nucleotide exchange factor mSec12

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (6)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-E70016 Terminal deoxyribonucleotidyltransferase Inhibitor / Unkown
HY-116170 SN34037 Inhibitor 99.02% Unkown
HY-RS11080 PREB Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-N16567 Acrofolione A / Unkown
HY-RS22286 Preb Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS28809 Preb Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Preb NCBI NCBI:10113