HDDC2 - HD domain containing 2 Gene

Also Known as C6orf74; CGI-130; NS5ATP2; dJ167O5.2

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 51020

About HDDC2

This gene has 10 transcripts (splice variants) and 214 orthologues. Ubiquitous expression in adrenal (RPKM 20.8), brain (RPKM 17.5) and 25 other tissues.

Summary

Predicted to enable 5'-deoxynucleotidase activity. Predicted to be involved in dephosphorylation. Predicted to be active in cytoplasm. [provided by Alliance of Genome Resources, Apr 2022]

HDDC2 Products (1)

mRNA Protein Name
NM_016063.3 NP_057147.2 5'-deoxynucleotidase HDDC2

Gene Ontology

  • Molecular Function
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
22190034 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

HDDC2 Protein Structure

HD_3

HD_3: HD domain (24 - 175)

  • 0
  • 100
  • 204 a.a.
Protein Preferred Names Protein Names

5'-deoxynucleotidase HDDC2

  • HCV NS5A-transactivated protein 2

HDDC2 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
HDDC2 Q7Z4H3 LCN2 Homo sapiens P80188
Y2H Prey Pooling
32296183
Intra
HDDC2 Q7Z4H3 LCN2 Homo sapiens P80188
Y2H Array
32296183
Intra
HDDC2 Q7Z4H3 POMC Homo sapiens P01189
Y2H Array
32296183
Intra
HDDC2 Q7Z4H3 POMC Homo sapiens P01189
Y2H Prey Pooling
32296183
Cross
HDDC2 Q7Z4H3 q76353_9hiv1 Human immunodeficiency virus Q76353
Pull Down
22190034
Intra
HDDC2 Q7Z4H3 IKBKG Homo sapiens Q9Y6K9
Y2H Array
32296183
Intra
HDDC2 Q7Z4H3 IKBKG Homo sapiens Q9Y6K9
Y2H Prey Pooling
32296183
Intra
HDDC2 Q7Z4H3 IKBKG Homo sapiens Q9Y6K9
Validated Y2H
32296183
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS06092 HDDC2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Felis catus HDDC2 VGNC VGNC:62771
Rattus norvegicus HDDC2 RGD RGD:1307562
Bos taurus HDDC2 VGNC VGNC:29785
Mus musculus HDDC2 MGD MGI:1916942
Macaca mulatta HDDC2 VGNC VGNC:73209
Canis familiaris HDDC2 VGNC VGNC:53723
Others HDDC2 NCBI