ATP5F1D - ATP synthase F1 subunit delta Gene

Homo sapiens

Also known as ATP5D; MC5DN5

Gene ID: 513 | Gene type: protein coding

About ATP5F1D

Cytogenetic location: 19p13.3 Genomic coordinates (GRCh38): 19:1,241,751-1,244,825 (from NCBI)

This gene has 9 transcripts (splice variants), 199 orthologues and is associated with 3 phenotypes. Ubiquitous expression in kidney (RPKM 30.9), colon (RPKM 30.8) and 25 other tissues.

Summary

This gene encodes a subunit of mitochondrial ATP Synthase. Mitochondrial ATP Synthase catalyzes ATP synthesis, utilizing an electrochemical gradient of protons across the inner membrane during oxidative phosphorylation. ATP Synthase is composed of two linked multi-subunit complexes: the soluble catalytic core, F1, and the membrane-spanning component, Fo, comprising the proton channel. The catalytic portion of mitochondrial ATP Synthase consists of 5 different subunits (alpha, beta, gamma, delta, and epsilon) assembled with a stoichiometry of 3 alpha, 3 beta, and a single representative of the other 3. The proton channel consists of three main subunits (a, b, c). This gene encodes the delta subunit of the catalytic core. Alternatively spliced transcript variants encoding the same isoform have been identified. [provided by RefSeq, Jul 2008]

ATP5F1D Products(2)

mRNA	Protein	Name
NM_001001975.2	NP_001001975.1	ATP synthase subunit delta, mitochondrial precursor
NM_001687.5	NP_001678.1	ATP synthase subunit delta, mitochondrial precursor

ATP5F1D Protein Structure

ATP-synt_DE_N

0
100
168 a.a.

Protein Preferred Names

Protein Names

ATP synthase subunit delta, mitochondrial

ATP synthase, H+ transporting, mitochondrial F1 complex, delta subunit

Recombinant ATP5F1D Proteins

Cat. No.	Product Name	Accession	Purity
HY-P72097	ATP5D Protein, Human (His-SUMO)	P30049 (A23-E168)	≥95%
HY-P72098	ATP5D Protein, Human (His)	P30049 (A23-E168)	≥95%

Related Diseases

Diseases

Alias

Mitochondrial Complex V Deficiency, Nuclear Type 5

Mitochondrial Complex V Deficiency	MC5DN5
Mitochondrial Complex V Deficiency, Atp5f1d Type	Mitochondrial Complex V Deficiency
Mitochondrial Complex 5 Deficiency Nuclear Type 5	Complex 5 Mitochondrial Respiratory Chain Deficiency
Atp Synthase Deficiency	Mitochondrial Complex V Deficiency, Nuclear Type 5
Complex V Deficiency

Isolated Atp Synthase Deficiency

Isolated Mitochondrial Respiratory Chain Complex V Deficiency

Mitochondrial Disease

Mitochondrial Diseases

Mitochondrial Disorder

3-Methylglutaconic Aciduria

3-Methyl Glutaconic Aciduria

Ciliary Dyskinesia, Primary, 30

Primary Ciliary Dyskinesia 30	CILD30
Ciliary Dyskinesia, Primary, 30, With Or Without Situs Inversus	Primary Ciliary Dyskinesia 30 Without Situs Inversus
Primary Ciliary Dyskinesia 30 With Or Without Situs Inversus	Dyskinesia, Ciliary, Primary, Type 30

Lactic Acidosis

Acidosis, Lactic

Acidosis Lactic

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS01205	ATP5F1D Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Felis catus	ATP5F1D	VGNC	VGNC:102003
Rattus norvegicus	ATP5F1D	RGD	RGD:621372
Macaca mulatta	ATP5F1D	VGNC	VGNC:108475
Canis familiaris	ATP5F1D	VGNC	VGNC:38264
Mus musculus	ATP5F1D	MGD	MGI:1913293
Bos taurus	ATP5F1D	VGNC	VGNC:26302

Name
Email *

	Sorry, but the email address you supplied was invalid.