2. Gene
  3. TAOK3 - TAO kinase 3 Gene

TAOK3 - TAO kinase 3 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Homo sapiens

Also known as DPK; JIK; hKFC-A; MAP3K18

Gene ID: 51347 | Gene type: protein coding

About TAOK3

Cytogenetic location: 12q24.23 Genomic coordinates (GRCh38): 12:118,149,801-118,372,907 (from NCBI)

This gene has 19 transcripts (splice variants), 299 orthologues and 35 paralogues. Ubiquitous expression in brain (RPKM 12.0), prostate (RPKM 9.7) and 25 other tissues.

Summary

The protein encoded by this gene is a serine/threonine protein kinase that activates the p38/MAPK14 stress-activated MAPK cascade but inhibits the basal activity of the MAPK8/JNK cascade. The encoded protein is a member of the GCK subfamily of STE20-like kinases. [provided by RefSeq, Oct 2016]

TAOK3 Products(12)

mRNA Protein Name
NM_001346487.2 NP_001333416.1 serine/threonine-protein kinase TAO3 isoform a
NM_001346488.2 NP_001333417.1 serine/threonine-protein kinase TAO3 isoform b
NM_001346489.2 NP_001333418.1 serine/threonine-protein kinase TAO3 isoform b
NM_001346490.2 NP_001333419.1 serine/threonine-protein kinase TAO3 isoform c
NM_001346491.2 NP_001333420.1 serine/threonine-protein kinase TAO3 isoform d
NM_001346492.2 NP_001333421.1 serine/threonine-protein kinase TAO3 isoform d
NM_001346493.2 NP_001333422.1 serine/threonine-protein kinase TAO3 isoform e
NM_001346494.2 NP_001333423.1 serine/threonine-protein kinase TAO3 isoform f
NM_001346495.2 NP_001333424.1 serine/threonine-protein kinase TAO3 isoform f
NM_001346496.2 NP_001333425.1 serine/threonine-protein kinase TAO3 isoform g
NM_001346497.2 NP_001333426.1 serine/threonine-protein kinase TAO3 isoform g
NM_016281.4 NP_057365.3 serine/threonine-protein kinase TAO3 isoform b

TAOK3 Protein Structure

Pkinase

Pkinase: Protein kinase domain (28 - 277)

  • 0
  • 200
  • 400
  • 600
  • 800
  • 898 a.a.
Protein Preferred Names Protein Names

serine/threonine-protein kinase TAO3

CTCL-associated antigen HD-CL-09

Recombinant TAOK3 Proteins

Cat. No. Product Name Accession Purity
HY-P77222 TAOK3 Protein, Human (sf9, His-GST) Q9H2K8 (M1-D411) ≥95%

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS14200 TAOK3 Human Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Bos taurus TAOK3 VGNC VGNC:35597
Canis familiaris TAOK3 VGNC VGNC:47104
Macaca mulatta TAOK3 VGNC VGNC:81593
Felis catus TAOK3 VGNC VGNC:80496
Mus musculus TAOK3 MGD MGI:3041177
Rattus norvegicus TAOK3 RGD RGD:1562861
Others TAOK3 NCBI