CYB5R1 - cytochrome b5 reductase 1 Gene

Homo sapiens

Also known as B5R1; B5R2; B5R.1; NQO3A2; humb5R2

Gene ID: 51706 | Gene type: protein coding

About CYB5R1

Cytogenetic location: 1q32.1 Genomic coordinates (GRCh38): 1:202,961,873-202,967,257 (from NCBI)

This gene has 7 transcripts (splice variants), 116 orthologues and 5 paralogues. Ubiquitous expression in skin (RPKM 57.6), heart (RPKM 53.8) and 25 other tissues.

Summary

Predicted to enable FAD binding activity. Predicted to be involved in bicarbonate transport. Located in extracellular exosome; membrane; and mitochondrion. [provided by Alliance of Genome Resources, Apr 2022]

CYB5R1 Products(1)

mRNA	Protein	Name
NM_016243.3	NP_057327.2	NADH-cytochrome b5 reductase 1

CYB5R1 Protein Structure

FAD_binding_6

NAD_binding_1

0
100
200
305 a.a.

Protein Preferred Names

Protein Names

NADH-cytochrome b5 reductase 1

NAD(P)H:quinone oxidoreductase type 3, polypeptide A2

Recombinant CYB5R1 Proteins

Cat. No.	Product Name	Accession	Purity
HY-P76856	CYB5R1 Protein, Human (His)	Q9UHQ9 (L29-Y305)	≥95%

Related Diseases

Diseases

Alias

De Quervain Disease

Radial Styloid Tenosynovitis	Tenosynovitis, De Quervain'S
De Quervain'S Disease	Tenosynovitis Of Radial Styloid Process
Stenosans Tenosynovitis

Methemoglobinemia

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS03419	CYB5R1 Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Macaca mulatta	CYB5R1	VGNC	VGNC:71398
Bos taurus	CYB5R1	VGNC	VGNC:97257
Canis familiaris	CYB5R1	VGNC	VGNC:50281
Mus musculus	CYB5R1	MGD	MGI:1919267
Rattus norvegicus	CYB5R1	RGD	RGD:1306084
Others	CYB5R1	NCBI

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