HIGD1C - HIG1 hypoxia inducible domain family member 1C Gene

Also Known as GM921

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 613227

Summary

Predicted to be involved in mitochondrial respirasome assembly. Predicted to act upstream of or within response to hypoxia. Predicted to be located in mitochondrial membrane. Predicted to be active in mitochondrion. [provided by Alliance of Genome Resources, Jul 2025]
Low expression observed in reference dataset.

HIGD1C Products (1)

mRNA Protein Name
NM_001109619.4 NP_001103089.1 HIG1 domain family member 1C

Gene Ontology

  • Molecular Function
Molecular Function GO Annotation Evidence Verweise Source
enables protein binding IPI
IPI: Inferred from physical interaction
32296183 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

HIGD1C Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method Verweise
Intra
HIGD1C A8MV81 SYT16 Homo sapiens Q17RD7
Validated Y2H
32296183
Intra
HIGD1C A8MV81 APOC1 Homo sapiens P02654
Validated Y2H
32296183
Intra
HIGD1C A8MV81 APOC1 Homo sapiens P02654
Y2H Array
32296183
Intra
HIGD1C A8MV81 APOC1 Homo sapiens P02654
Y2H Prey Pooling
32296183
Intra
HIGD1C A8MV81 FARS2 Homo sapiens O95363
Validated Y2H
32296183
Intra
HIGD1C A8MV81 RBFA Homo sapiens Q8N0V3
Validated Y2H
32296183
Intra
HIGD1C A8MV81 CIDEB Homo sapiens Q9UHD4
Validated Y2H
32296183
Intra
HIGD1C A8MV81 CIDEB Homo sapiens Q9UHD4
Y2H Prey Pooling
32296183
Intra
HIGD1C A8MV81 CIDEB Homo sapiens Q9UHD4
Y2H Array
32296183
Intra
HIGD1C A8MV81 TCEA2 Homo sapiens Q15560
Validated Y2H
32296183
Intra
HIGD1C A8MV81 NTAQ1 Homo sapiens Q96HA8
Validated Y2H
32296183
Intra
HIGD1C A8MV81 PBX3 Homo sapiens Q96AL5
Validated Y2H
32296183
Intra
HIGD1C A8MV81 MTERF3 Homo sapiens Q96E29
Validated Y2H
32296183
Intra
HIGD1C A8MV81 TMEM14B Homo sapiens Q9NUH8
Validated Y2H
32296183
Intra
HIGD1C A8MV81 TMEM14B Homo sapiens Q9NUH8
Y2H Array
32296183
Intra
HIGD1C A8MV81 TMEM14B Homo sapiens Q9NUH8
Y2H Prey Pooling
32296183
Intra
HIGD1C A8MV81 GAD2 Homo sapiens Q05329
Validated Y2H
32296183
Intra
HIGD1C A8MV81 CYB5R1 Homo sapiens Q9UHQ9
Validated Y2H
32296183
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (6)
Art. -Nr. Produktname
Wirkung
Reinheit
Rare Diseases
HY-RS06171 HIGD1A Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS06172 HIGD1B Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS16264 HIGD1B Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS16297 Higd1b Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS21864 Higd1a Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS28381 Higd1a Rat Pre-designed siRNA Set A Pre-designed Set / Unkown