2. Gene
  3. HDAC4 - histone deacetylase 4 Gene

HDAC4 - histone deacetylase 4 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Bos taurus
Gene ID: 517559 | Gene type: protein coding

About HDAC4

Primary_assembly 3: 118,225,398-118,462,734 reverse strand.ARS-UCD1.2:CM008170.2

This gene has 3 transcripts (splice variants), 263 orthologues and 10 paralogues.

HDAC4 Products(9)

mRNA Protein Name
XM_024990279.1 XP_024846047.1 histone deacetylase 4 isoform X3
XM_024990283.1 XP_024846051.1 histone deacetylase 4 isoform X6
XM_024990277.1 XP_024846045.1 histone deacetylase 4 isoform X1
XM_024990281.1 XP_024846049.1 histone deacetylase 4 isoform X5
XM_024990285.1 XP_024846053.1 histone deacetylase 4 isoform X6
XM_024990282.1 XP_024846050.1 histone deacetylase 4 isoform X5
XM_024990280.1 XP_024846048.1 histone deacetylase 4 isoform X4
XM_024990278.1 XP_024846046.1 histone deacetylase 4 isoform X2
XM_024990284.1 XP_024846052.1 histone deacetylase 4 isoform X6

HDAC4 Protein Structure

ClassIIa_HDAC4_Gln-rich-N

ClassIIa_HDAC4_Gln-rich-N: cd10162 (132 - 196)

PHA03247

PHA03247: cl33720 (260 - 604)

HDAC4

HDAC4: cd10006 (731 - 1139)

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  • 1167 a.a.
Protein Preferred Names Protein Names

histone deacetylase 4

Related Agents

Approval
Bioactive Molecules (5)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-15149 Romidepsin Inhibitor 99.98% Unkown
HY-14842 Givinostat Inhibitor 98.67% Yes
HY-13322 Pracinostat Inhibitor 99.80% Yes
HY-14842B Givinostat hydrochloride monohydrate Inhibitor 99.63% Yes
HY-14842A Givinostat hydrochloride Inhibitor 98.06% Yes
Clinical Phase
Bioactive Molecules (6)
Cat. No. Product Name Effect
Purity Phase
HY-10528 Tasquinimod Modulator 99.70% Phase 3
HY-16026 Ricolinostat Inhibitor 99.83% Phase 2
HY-15433 Quisinostat Inhibitor 99.71% Phase 2
HY-13522 Fimepinostat Inhibitor 99.95% Phase 2
HY-15433A Quisinostat dihydrochloride Inhibitor 99.05% Phase 2
HY-10223 CUDC-101 Inhibitor 99.05% Phase 1
Pre-clinical Phase
Bioactive Molecules (57)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-18361 TMP195 Inhibitor 99.82% Unkown
HY-13428 Tubacin Inhibitor 97.11% Unkown
HY-18998 LMK-235 Inhibitor 99.61% Unkown
HY-18360 TMP269 Inhibitor 98.16% Unkown
HY-16699 Nexturastat A Inhibitor 98.28% Unkown
HY-119939 CHDI-390576 Inhibitor 98.10% Unkown
HY-19350 BML-210 Inhibitor 98.04% Unkown
HY-115475 SW-100 Inhibitor 99.93% Unkown
HY-123295 HDAC3-IN-T247 Inhibitor 98.91% Unkown
HY-169259 HDAC9-IN-1 Inhibitor 95.13% Unkown
HY-150109 Purinostat mesylate Inhibitor 99.45% Unkown
HY-135714 Bavarostat Inhibitor 99.51% Unkown
HY-149285 NT160 Inhibitor 99.58% Unkown
HY-146153 HDAC-IN-40 Inhibitor 98.71% Unkown
HY-12954 PTACH Inhibitor 99.65% Unkown
HY-157740 XSJ-10 Inhibitor 95.16% Unkown
HY-117554 BRD9757 Inhibitor 99.75% Unkown
HY-149208 HDAC-IN-53 Inhibitor 95.73% Unkown
HY-148624 CHDI-00484077 Inhibitor 98.38% Unkown
HY-146678 HDAC6-IN-5 Inhibitor / Unkown
HY-146679 HDAC6-IN-6 Inhibitor / Unkown
HY-170379 HDAC-IN-84 Inhibitor / Unkown
HY-162630 HDAC6-IN-44 Inhibitor / Unkown
HY-152226 MC2590 Inhibitor 98.71% Unkown
HY-151897 HDAC-IN-49 Inhibitor / Unkown
HY-181086 FLT3/HDAC-IN-3 Inhibitor / Unkown
HY-149372 HDAC6-IN-17 Inhibitor / Unkown
HY-146159 PI3K/HDAC-IN-2 Inhibitor / Unkown
HY-149721 HDAC4-IN-1 Inhibitor / Unkown
HY-174302 PIM-1/HDAC-IN-2 Inhibitor / Unkown
HY-175030 TNI-97 Inhibitor / Unkown
HY-172159 FF2039 Inhibitor / Unkown
HY-124946 C1A Inhibitor / Unkown
HY-146684 HDAC-IN-36 Inhibitor / Unkown
HY-176868 Rodin-C Inhibitor / Unkown
HY-181579 HDAC6-IN-74 Inhibitor / Unkown
HY-143233 PIM-1/HDAC-IN-1 Inhibitor / Unkown
HY-179227 HDAC6 ligand-7 Inhibitor / Unkown
HY-149283 JAK/HDAC-IN-2 Inhibitor / Unkown
HY-152225 MC2625 Inhibitor / Unkown
HY-15433B Quisinostat hydrochloride Inhibitor / Unkown
HY-163143 HDAC8-IN-6 Inhibitor / Unkown
HY-179321 PROTAC HDAC4 Degrader-1 Degrader / Unkown
HY-150595 HDAC6-IN-10 Inhibitor / Unkown
HY-161778 ZG-126 Inhibitor / Unkown
HY-15144B (S)-Trichostatin A Inhibitor / Unkown
HY-169400 HDACs/EZH2-IN-1 Inhibitor / Unkown
HY-178022 HDAC6-IN-63 Inhibitor / Unkown
HY-147934 HDAC8-IN-3 Inhibitor / Unkown
HY-151263 G4/HDAC-IN-1 Inhibitor / Unkown
HY-150503 KH-259 Inhibitor / Unkown
HY-183560 HDAC6-IN-82 Inhibitor / Unkown
HY-151896 HDAC6-IN-14 Inhibitor / Unkown
HY-163803 CM-444 Inhibitor / Unkown
HY-182747 HDAC6-IN-79 Inhibitor / Unkown
HY-180214 HDAC6-IN-69 Inhibitor / Unkown
HY-P2044 Azumamide E Inhibitor / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens HDAC4 NCBI NCBI:9759