HDAC4 - histone deacetylase 4 Gene
Species: Bos taurus
Gene Type: protein coding
Gene ID: 517559
About HDAC4
Primary_assembly 3: 118,225,398-118,462,734 reverse strand.ARS-UCD1.2:CM008170.2
This gene has 3 transcripts (splice variants), 263 orthologues and 10 paralogues.
HDAC4 Products (9)
| mRNA | Protein | Name |
|---|---|---|
| XM_024990279.1 | XP_024846047.1 | histone deacetylase 4 isoform X3 |
| XM_024990283.1 | XP_024846051.1 | histone deacetylase 4 isoform X6 |
| XM_024990277.1 | XP_024846045.1 | histone deacetylase 4 isoform X1 |
| XM_024990281.1 | XP_024846049.1 | histone deacetylase 4 isoform X5 |
| XM_024990285.1 | XP_024846053.1 | histone deacetylase 4 isoform X6 |
| XM_024990282.1 | XP_024846050.1 | histone deacetylase 4 isoform X5 |
| XM_024990280.1 | XP_024846048.1 | histone deacetylase 4 isoform X4 |
| XM_024990278.1 | XP_024846046.1 | histone deacetylase 4 isoform X2 |
| XM_024990284.1 | XP_024846052.1 | histone deacetylase 4 isoform X6 |
HDAC4 Protein Structure
ClassIIa_HDAC4_Gln-rich-N
ClassIIa_HDAC4_Gln-rich-N: cd10162 (132 - 196)
PHA03247
PHA03247: cl33720 (260 - 604)
HDAC4
HDAC4: cd10006 (731 - 1139)
- 0
- 200
- 400
- 600
- 800
- 1000
- 1167 a.a.
| Protein Preferred Names | Protein Names | |
|---|---|---|
|
histone deacetylase 4 |
|
Related Agents
- Approval
- Clinical Phase
- Pre-clinical Phase
Approval
Bioactive Molecules
(5)
| Cat. No. | Product Name |
Effect
|
Purity |
Rare Diseases
|
|---|---|---|---|---|
| HY-15149 | Romidepsin | Inhibitor | 99.98% | Unkown |
| HY-14842 | Givinostat | Inhibitor | 98.67% | Yes |
| HY-13322 | Pracinostat | Inhibitor | 99.80% | Yes |
| HY-14842B | Givinostat hydrochloride monohydrate | Inhibitor | 99.63% | Yes |
| HY-14842A | Givinostat hydrochloride | Inhibitor | 98.06% | Yes |
Clinical Phase
Bioactive Molecules
(6)
| Cat. No. | Product Name |
Effect
|
Purity |
Phase
|
|---|---|---|---|---|
| HY-10528 | Tasquinimod | Modulator | 99.70% | Phase 3 |
| HY-16026 | Ricolinostat | Inhibitor | 99.83% | Phase 2 |
| HY-15433 | Quisinostat | Inhibitor | 99.71% | Phase 2 |
| HY-13522 | Fimepinostat | Inhibitor | 99.95% | Phase 2 |
| HY-15433A | Quisinostat dihydrochloride | Inhibitor | 99.05% | Phase 2 |
| HY-10223 | CUDC-101 | Inhibitor | 99.05% | Phase 1 |
Pre-clinical Phase
Bioactive Molecules
(60)
| Cat. No. | Product Name |
Effect
|
Purity |
Rare Diseases
|
|---|---|---|---|---|
| HY-18361 | TMP195 | Inhibitor | 99.82% | Unkown |
| HY-13428 | Tubacin | Inhibitor | 97.11% | Unkown |
| HY-18998 | LMK-235 | Inhibitor | 99.61% | Unkown |
| HY-18360 | TMP269 | Inhibitor | 98.16% | Unkown |
| HY-16699 | Nexturastat A | Inhibitor | 98.69% | Unkown |
| HY-19350 | BML-210 | Inhibitor | 98.04% | Unkown |
| HY-119939 | CHDI-390576 | Inhibitor | 98.10% | Unkown |
| HY-115475 | SW-100 | Inhibitor | 99.93% | Unkown |
| HY-123295 | HDAC3-IN-T247 | Inhibitor | 98.91% | Unkown |
| HY-169259 | HDAC9-IN-1 | Inhibitor | 95.13% | Unkown |
| HY-150109 | Purinostat mesylate | Inhibitor | 99.45% | Unkown |
| HY-135714 | Bavarostat | Inhibitor | 99.51% | Unkown |
| HY-149285 | NT160 | Inhibitor | 99.58% | Unkown |
| HY-W039803 | HDAC4 ligand-2 | Ligand | / | Unkown |
| HY-146153 | HDAC-IN-40 | Inhibitor | 98.71% | Unkown |
| HY-12954 | PTACH | Inhibitor | 99.65% | Unkown |
| HY-149721 | HDAC4-IN-1 | Inhibitor | 98.11% | Unkown |
| HY-148624 | CHDI-00484077 | Inhibitor | 98.38% | Unkown |
| HY-149208 | HDAC-IN-53 | Inhibitor | 95.73% | Unkown |
| HY-184524 | PROTAC HDAC4 Degrader-2 | / | Unkown | |
| HY-157740 | XSJ-10 | Inhibitor | 95.16% | Unkown |
| HY-117554 | BRD9757 | Inhibitor | 99.75% | Unkown |
| HY-146678 | HDAC6-IN-5 | Inhibitor | / | Unkown |
| HY-146679 | HDAC6-IN-6 | Inhibitor | / | Unkown |
| HY-161778 | ZG-126 | Inhibitor | / | Unkown |
| HY-179321 | PROTAC HDAC4 Degrader-1 | Degrader | / | Unkown |
| HY-150595 | HDAC6-IN-10 | Inhibitor | / | Unkown |
| HY-178022 | HDAC6-IN-63 | Inhibitor | / | Unkown |
| HY-151896 | HDAC6-IN-14 | Inhibitor | / | Unkown |
| HY-151263 | G4/HDAC-IN-1 | Inhibitor | / | Unkown |
| HY-149372 | HDAC6-IN-17 | Inhibitor | / | Unkown |
| HY-146159 | PI3K/HDAC-IN-2 | Inhibitor | / | Unkown |
| HY-150503 | KH-259 | Inhibitor | / | Unkown |
| HY-175030 | TNI-97 | Inhibitor | / | Unkown |
| HY-163803 | CM-444 | Inhibitor | / | Unkown |
| HY-176868 | Rodin-C | Inhibitor | / | Unkown |
| HY-146684 | HDAC-IN-36 | Inhibitor | / | Unkown |
| HY-170379 | HDAC-IN-84 | Inhibitor | / | Unkown |
| HY-152225 | MC2625 | Inhibitor | / | Unkown |
| HY-162630 | HDAC6-IN-44 | Inhibitor | / | Unkown |
| HY-163143 | HDAC8-IN-6 | Inhibitor | / | Unkown |
| HY-151897 | HDAC-IN-49 | Inhibitor | / | Unkown |
| HY-152226 | MC2590 | Inhibitor | 98.71% | Unkown |
| HY-181086 | FLT3/HDAC-IN-3 | Inhibitor | / | Unkown |
| HY-184203 | SM-06-09 | Inhibitor | / | Unkown |
| HY-15144B | (S)-Trichostatin A | Inhibitor | / | Unkown |
| HY-143233 | PIM-1/HDAC-IN-1 | Inhibitor | / | Unkown |
| HY-169400 | HDACs/EZH2-IN-1 | Inhibitor | / | Unkown |
| HY-174302 | PIM-1/HDAC-IN-2 | Inhibitor | / | Unkown |
| HY-147934 | HDAC8-IN-3 | Inhibitor | / | Unkown |
| HY-172159 | FF2039 | Inhibitor | / | Unkown |
| HY-181579 | HDAC6-IN-74 | Inhibitor | / | Unkown |
| HY-183560 | HDAC6-IN-82 | Inhibitor | / | Unkown |
| HY-124946 | C1A | Inhibitor | / | Unkown |
| HY-149283 | JAK/HDAC-IN-2 | Inhibitor | / | Unkown |
| HY-15433B | Quisinostat hydrochloride | Inhibitor | / | Unkown |
| HY-180214 | HDAC6-IN-69 | Inhibitor | / | Unkown |
| HY-179227 | HDAC6 ligand-7 | Inhibitor | / | Unkown |
| HY-182747 | HDAC6-IN-79 | Inhibitor | / | Unkown |
| HY-P2044 | Azumamide E | Inhibitor | / | Unkown |
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