2. Cell Cycle/DNA Damage Epigenetics
  3. HDAC
  4. HDAC8-IN-6

HDAC8-IN-6 (compound 3) is a potent HDAC8 inhibitor with an IC50 of 5.1 μM. HDAC8-IN-6 shows cytotoxicity.

For research use only. We do not sell to patients.

HDAC8-IN-6 Chemical Structure

HDAC8-IN-6 Chemical Structure

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HDAC8-IN-6 Related Antibodies

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Description

HDAC8-IN-6 (compound 3) is a potent HDAC8 inhibitor with an IC50 of 5.1 μM. HDAC8-IN-6 shows cytotoxicity[1].

IC50 & Target[1]

HDAC8

5.1 μM (IC50)

HDAC4

23.1 μM (IC50)

Molecular Weight

447.27

Formula

C19H18IN3O2
SMILES

C[N+]1=CC=C(NC(CC(N2CC3=C(C=CC=C3)C2)=O)=O)C(C#C)=C1.[I-]
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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HDAC8-IN-6 Related Classifications

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The molarity calculator equation

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

HDAC8-IN-6HDACHistone deacetylasesTHP-1HL-60cytotoxicityInhibitorinhibitorinhibit

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