PNLIPRP2 - pancreatic lipase related protein 2 (gene/pseudogene) Gene

Also Known as PLRP2

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 5408

About PNLIPRP2

Cytogenetic location: 10q25.3 Genomic coordinates (GRCh38): 10:116,620,953-116,645,143 (from NCBI)

This gene has 3 transcripts (splice variants), 248 orthologues and 9 paralogues. Restricted expression toward pancreas (RPKM 1148.7).

Summary

This gene encodes a Lipase that hydrolyzes galactolipids, the main components of plant membrane lipids. An allelic polymorphism in this gene results in both coding and non-coding variants; the reference genome represents the non-coding allele. [provided by RefSeq, Aug 2015]

PNLIPRP2 Products (1)

mRNA Protein Name
NM_005396.5 NP_005387.3 pancreatic lipase-related protein 2 precursor

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables calcium ion binding IDA
IDA: Inferred from direct assay
18702514 GOA
enables galactolipase activity IDA
IDA: Inferred from direct assay
15287741 GOA
enables monoacylglycerol lipase activity IDA
IDA: Inferred from direct assay
17401110 GOA
enables phospholipase activity IDA
IDA: Inferred from direct assay
17401110 GOA
enables protein binding IPI
IPI: Inferred from physical interaction
33961781 GOA
enables triacylglycerol lipase activity IDA
IDA: Inferred from direct assay
15287741 GOA
Biological Process GO Annotation Evidence References Source
involved in galactolipid catabolic process IDA
IDA: Inferred from direct assay
15287741 GOA
involved in phosphatidylcholine catabolic process IDA
IDA: Inferred from direct assay
17401110 GOA
involved in phospholipid catabolic process IDA
IDA: Inferred from direct assay
18702514 GOA
involved in triglyceride catabolic process IDA
IDA: Inferred from direct assay
15287741 GOA
Cellular Component GO Annotation Evidence References Source
located in extracellular space IDA
IDA: Inferred from direct assay
18702514 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

pancreatic lipase-related protein 2

  • PL-RP2

PNLIPRP2 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
PNLIPRP2 P54317 EDC3 Homo sapiens Q96F86
Anti Tag CoIP
33961781
Cross: Cross-species interaction Intra: Intraspecies interaction

Recombinant PNLIPRP2 Proteins

Cat. No. Product Name Accession Purity
HY-P70972 PNLIPRP2 Protein, Human (HEK293, His) AAH05989.1 (K18-C469) ≥ 95%, as determined by reducing SDS-PAGE.
HY-P77149 PNLIPRP2 Protein, Human (sf9, His) P54317 (K18-C469) ≥ 95%, as determined by reducing SDS-PAGE.

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS10782 PNLIPRP2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS21276 Pnliprp2 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS27795 Pnliprp2 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Mus musculus PNLIPRP2 MGD MGI:1336202
Canis familiaris PNLIPRP2 VGNC VGNC:53009
Macaca mulatta PNLIPRP2 VGNC VGNC:106089
Rattus norvegicus PNLIPRP2 RGD RGD:620793