2. Gene
  3. UBE2R2 - ubiquitin conjugating enzyme E2 R2 Gene

UBE2R2 - ubiquitin conjugating enzyme E2 R2 Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as UBC3B; CDC34B; E2-CDC34B

Gene ID: 54926 | Gene type: protein coding

About UBE2R2

Cytogenetic location: 9p13.3 Genomic coordinates (GRCh38): 9:33,815,168-33,920,399 (from NCBI)

This gene has 1 transcript (splice variant), 137 orthologues and 24 paralogues. Ubiquitous expression in testis (RPKM 25.6), endometrium (RPKM 16.9) and 25 other tissues.

Summary

Protein kinase CK2 is a ubiquitous and pleiotropic Ser/Thr protein kinase involved in cell growth and transformation. This gene encodes a protein similar to the E2 ubiquitin conjugating Enzyme UBC3/CDC34. Studies suggest that CK2-dependent phosphorylation of this ubiquitin-conjugating Enzyme functions by regulating beta-TrCP substrate recognition and induces its interaction with beta-TrCP, enhancing beta-catenin degradation. [provided by RefSeq, Jul 2008]

UBE2R2 Products(1)

mRNA Protein Name
NM_017811.4 NP_060281.2 ubiquitin-conjugating enzyme E2 R2

UBE2R2 Protein Structure

UQ_con

UQ_con: Ubiquitin-conjugating enzyme (13 - 153)

  • 0
  • 100
  • 200
  • 238 a.a.
Protein Preferred Names Protein Names

ubiquitin-conjugating enzyme E2 R2

E2 ubiquitin-conjugating enzyme R2

Recombinant UBE2R2 Proteins

Cat. No. Product Name Accession Purity
HY-P71407 UBE2R2 Protein, Human (His) Q712K3 (M1-S238) ≥95%

Related Diseases

Diseases Alias
Clear Cell Adenofibroma

Cystadenofibroma
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS15360 UBE2R2 Human Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Mus musculus UBE2R2 MGD MGI:1914865
Bos taurus UBE2R2 VGNC VGNC:36594
Canis familiaris UBE2R2 VGNC VGNC:48064
Rattus norvegicus UBE2R2 RGD RGD:1594826
Others UBE2R2 NCBI