ASF1B - anti-silencing function 1B histone chaperone Gene

Homo sapiens

Also known as CIA-II

Gene ID: 55723 | Gene type: protein coding

About ASF1B

Cytogenetic location: 19p13.12 Genomic coordinates (GRCh38): 19:14,119,512-14,136,589 (from NCBI)

This gene has 5 transcripts (splice variants), 1 gene allele, 265 orthologues and 1 paralogue. Biased expression in testis (RPKM 18.2), lymph node (RPKM 12.4) and 13 other tissues.

Summary

This gene encodes a member of the H3/H4 family of histone chaperone proteins and is similar to the anti-silencing function-1 gene in yeast. The encoded protein is the substrate of the tousled-like kinase family of cell cycle-regulated kinases, and may play a key role in modulating the nucleosome structure of chromatin by ensuring a constant supply of histones at sites of nucleosome assembly. [provided by RefSeq, Jul 2008]

ASF1B Products(1)

mRNA	Protein	Name
NM_018154.3	NP_060624.1	histone chaperone ASF1B

ASF1B Protein Structure

ASF1_hist_chap

0
100
202 a.a.

Protein Preferred Names

Protein Names

histone chaperone ASF1B

ASF1 anti-silencing function 1 homolog B

Recombinant ASF1B Proteins

Cat. No.	Product Name	Accession	Purity
HY-P76157	ASF1B Protein, Human (sf9, His)	Q9NVP2 (M1-I202)	≥95%

Related Diseases

Diseases

Alias

Luminal Breast Carcinoma A

Breast Tumor Luminal	Luminal A Breast Carcinoma
Luminal Breast Cancer

Anemia, Congenital Dyserythropoietic, Type Ia

Congenital Dyserythropoietic Anemia Type I	Cda I
CDAN1A	Congenital Dyserythropoietic Anemia Type 1
Congenital Dyserythropoietic Anemia Type Ia	Congenital Dyserythropoietic Anemia, Type I
Anemia, Congenital Dyserythropoietic, Type I	Cda Type 1
Cda Type I	Cda Ia
Dyserythropoietic Anemia, Congenital Type 1	Anemia, Congenital Dyserythropoietic, Type 1a
Dyserythropoietic Anemia, Congenital, Type Ia	Cda, Type Ia
Congenital Dyserythropoietic Anaemia Type 1	Congenital Dyserythropoietic Anaemia Type I
Anemia, Dyserythropoietic, Congenital Type 1	Type I Congenital Dyserythropoietic Anemia
Anemia, Congenital Dyserythropoietic, 1a	Anemia, Dyserythropoietic, Congenital, Type Ia

Cataract 34, Multiple Types

Cataract, Autosomal Recessive Congenital 3	Cataract 34 Multiple Types
CTRCT34	Catc3
Cataract 34, Multiple Types, With Or Without Microcornea	Autosomal Recessive Congenital Cataract 3
Cataract 34 Multiple Types With Or Without Microcornea	Cataract, Multiple Types, Type 34

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS01084	ASF1B Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Mus musculus	ASF1B	MGD	MGI:1914179
Macaca mulatta	ASF1B	VGNC	VGNC:69872
Felis catus	ASF1B	VGNC	VGNC:59969
Bos taurus	ASF1B	VGNC	VGNC:50605
Rattus norvegicus	ASF1B	RGD	RGD:1304918
Others	ASF1B	NCBI

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