TRPC7 - transient receptor potential cation channel subfamily C member 7 Gene

Homo sapiens

Also known as TRP7

Gene ID: 57113 | Gene type: protein coding

About TRPC7

This gene has 7 transcripts (splice variants), 226 orthologues and 5 paralogues. Low expression observed in reference dataset.

Summary

Predicted to enable inositol 1,4,5 trisphosphate binding activity and store-operated Calcium Channel activity. Predicted to be involved in metal ion transport; regulation of cytosolic calcium ion concentration; and single fertilization. Predicted to act upstream of or within calcium ion transport. Predicted to be located in plasma membrane. Predicted to be part of cation channel complex. Predicted to be integral component of plasma membrane. [provided by Alliance of Genome Resources, Apr 2022]

TRPC7 Products(4)

mRNA	Protein	Name
NM_001167576.2	NP_001161048.1	short transient receptor potential channel 7 isoform 3
NM_001167577.2	NP_001161049.1	short transient receptor potential channel 7 isoform 2
NM_001376901.1	NP_001363830.1	short transient receptor potential channel 7 isoform 4
NM_020389.3	NP_065122.1	short transient receptor potential channel 7 isoform 1

TRPC7 Protein Structure

Ank_2

TRP_2

Ion_trans

0
200
400
600
800
862 a.a.

Protein Preferred Names

Protein Names

short transient receptor potential channel 7

likley ortholog of mouse transient receptor potential cation channel, subfamily C, member 7

Related Agents

Pre-clinical Phase

Bioactive Molecules (3)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-111925	BI-749327	Antagonist	99.50%	Unkown
HY-162090	TRPC antagonist 1	Antagonist	/	Unkown
HY-RS15110	TRPC7 Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Rattus norvegicus	TRPC7	RGD	RGD:628820
Bos taurus	TRPC7	VGNC	VGNC:36387
Canis familiaris	TRPC7	VGNC	VGNC:47872
Mus musculus	TRPC7	MGD	MGI:1349470
Felis catus	TRPC7	VGNC	VGNC:66587
Macaca mulatta	TRPC7	VGNC	VGNC:79280

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