Ereg - epiregulin Gene

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 59325

Summary

Enables growth factor activity. Involved in several processes, including female gamete generation; positive regulation of macromolecule metabolic process; and positive regulation of mitotic nuclear division. Located in extracellular space. Human ortholog(s) of this gene implicated in extrapulmonary tuberculosis; pulmonary tuberculosis; and tuberculosis. Orthologous to human EREG (Epiregulin). [provided by Alliance of Genome Resources, Apr 2022]

Ereg Products (1)

mRNA Protein Name
NM_021689.1 NP_067721.1 proepiregulin preproprotein

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables growth factor activity IDA
IDA: Inferred from direct assay
9990076 RGD
Biological Process GO Annotation Evidence References Source
involved in epidermal growth factor receptor signaling pathway IDA
IDA: Inferred from direct assay
9990076 RGD
involved in female meiotic nuclear division IDA
IDA: Inferred from direct assay
15459120 RGD
involved in luteinizing hormone signaling pathway IDA
IDA: Inferred from direct assay
15459120 RGD
involved in oocyte maturation IDA
IDA: Inferred from direct assay
15459120 RGD
involved in ovarian cumulus expansion IDA
IDA: Inferred from direct assay
15459120 RGD
involved in ovulation IDA
IDA: Inferred from direct assay
15459120 RGD
involved in positive regulation of DNA replication IDA
IDA: Inferred from direct assay
9990076 RGD
involved in positive regulation of cell population proliferation IDA
IDA: Inferred from direct assay
9990076 RGD
involved in positive regulation of mitotic nuclear division IDA
IDA: Inferred from direct assay
9990076 RGD
involved in positive regulation of smooth muscle cell proliferation IDA
IDA: Inferred from direct assay
9990076 RGD
involved in positive regulation of smooth muscle cell proliferation IMP
IMP: Inferred from mutant phenotype
14570897 RGD
involved in primary follicle stage IDA
IDA: Inferred from direct assay
15459120 RGD
involved in response to peptide hormone IEP
IEP: Inferred from expression pattern
15459120 RGD
Cellular Component GO Annotation Evidence References Source
located in extracellular space IDA
IDA: Inferred from direct assay
14570897 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

proepiregulin

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (4)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS04487 EREG Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS16966 Ereg Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-174716 Human EREG mRNA / Unkown
HY-RS23409 Ereg Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
Bioactive MoleculesInhibitory Antibodies (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-P992137 Turigrobart Inhibitor 99.9% Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Ereg NCBI NCBI:2069