Pawr - pro-apoptotic WT1 regulator Gene

Also Known as Par4; Par-4

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 64513

Summary

Enables actin binding activity; protein kinase C binding activity; and protein Phosphatase 1 binding activity. Involved in several processes, including detection of stimulus involved in sensory perception of pain; positive regulation of hydrolase activity; and regulation of cellular extravasation. Located in axon; cytoplasm; and neuronal cell body. Colocalizes with actin filament. Biomarker of mental depression; middle cerebral artery infarction; transient cerebral ischemia; and visual epilepsy. Orthologous to human PAWR (pro-apoptotic WT1 regulator). [provided by Alliance of Genome Resources, Apr 2022]

Pawr Products (1)

mRNA Protein Name
NM_033485.3 NP_277020.2 PRKC apoptosis WT1 regulator protein
Protein Preferred Names Protein Names

PRKC apoptosis WT1 regulator protein

  • PRKC, apoptosis, WT1, regulator

  • Prostate apoptosis response protein 4

  • par-4 induced by effectors of apoptosis

  • prostate apoptosis response 4 protein

  • transcriptional repressor Par-4-like protein PAWR

Pawr Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
Pawr Q62627 Tfpt Rattus norvegicus Q9JMG6
Anti Tag CoIP
16229834
Intra
Pawr Q62627 Tfpt Rattus norvegicus Q9JMG6
Y2H
16229834
Intra
Pawr Q62627 Tfpt Rattus norvegicus Q9JMG6
Anti Bait CoIP
16229834
Intra
Pawr Q62627 Tfpt Rattus norvegicus Q9JMG6
Pull Down
16229834
Cross
Pawr Q62627 HSPA5 Homo sapiens P11021
Pull Down
19632185
Intra
Pawr Q62627 Dapk3 Rattus norvegicus O88764
Protein Kinase Assay
10602480
Intra
Pawr Q62627 Dapk3 Rattus norvegicus O88764
IF
10602480
Intra
Pawr Q62627 Dapk3 Rattus norvegicus O88764
Y2H
10602480
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. 상품명
효과
Purity
Rare Diseases
HY-RS10087 PAWR Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS21400 Pawr Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS27919 Pawr Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Pawr NCBI NCBI:5074