ANXA8 - annexin A8 Gene

Homo sapiens

Also known as ANX8; CH17-360D5.2

Gene ID: 653145 | Gene type: protein coding

About ANXA8

Cytogenetic location: 10q11.22 Genomic coordinates (GRCh38): 10:47,467,993-47,991,796 (from NCBI)

This gene has 8 transcripts (splice variants), 336 orthologues and 12 paralogues. Biased expression in skin (RPKM 96.8), esophagus (RPKM 57.8) and 3 other tissues.

Summary

This gene encodes a member of the annexin family of evolutionarily conserved Ca2+ and phospholipid binding proteins. The encoded protein may function as an an anticoagulant that indirectly inhibits the thromboplastin-specific complex. Overexpression of this gene has been associated with acute myelocytic leukemia. A highly similar duplicated copy of this gene is found in close proximity on the long arm of chromosome 10. [provided by RefSeq, Jul 2008]

ANXA8 Products(3)

mRNA	Protein	Name
NM_001040084.3	NP_001035173.1	annexin A8 isoform 2
NM_001271702.2	NP_001258631.1	annexin A8 isoform 1
NM_001271703.2	NP_001258632.1	annexin A8 isoform 3

ANXA8 Protein Structure

Annexin

0
100
200
300
327 a.a.

Protein Preferred Names

Protein Names

annexin A8

VAC-beta

Recombinant ANXA8 Proteins

Cat. No.	Product Name	Accession	Purity
HY-P7520	Annexin A8/ANXA8 Protein, Human	P13928 (M1-P327)	≥95%
HY-P75505	Annexin A8/ANXA8 Protein, Human (His)	P13928 (M1-P327)	≥95%

Related Diseases

Diseases

Alias

Breast Adenocarcinoma

Mammary Adenocarcinoma

Adenocarcinoma Of Breast

Metagonimiasis

Trematode Infections	Infection By Metagonimus Yokogawai
Metagonimus Yokogawai Infection

Heterophyiasis

Heterophyes Infectious Disease

Acute Laryngopharyngitis

Pharyngolaryngitis	Laryngopharyngitis
Hypopharyngitis

Trachea Leiomyoma

Tracheal Neoplasms	Leiomyoma Of The Trachea
Tracheal Neoplasm	Tracheal Leiomyoma

Aortic Aneurysm, Familial Abdominal, 1

Abdominal Aortic Aneurysm	Aortic Aneurysm, Familial Abdominal 1
Aneurysm, Abdominal Aortic	AAA
Aortic Aneurysm, Abdominal	AAA1
Aortic Aneurysm, Familial Abdominal	Aortic Aneurysm Abdominal
Abdominal Aortic Aneurysms	Abdominal Aortic Aneurysm Without Mention Of Perforation Or Rupture
Abdomen Aneurysm	Abdominal Aorta Aneurysm
Aneurysm Of Abdominal Aorta	Aortic Abdomen Aneurysm
Aaa - [Abdominal Aortic Aneurysm]	Abdominal Aneurysm
Abdominal Aorta Aneurysm Rupture	Abdominal Aorta Aneurysm Ruptured
Abdominal Aortic Aneurysm Which Has Ruptured	Ruptured Aaa
Abdomen Aorta Aneurysm Ruptured	Abdomen Aorta Rupture
Abdomen Aortic Aneurysm Rupture	Abdomen Aneurysm Rupture
Abdomen Aortic Aneurysm Ruptured	Abdomen Aortic Rupture
Abdominal Aorta Rupture	Abdominal Aortic Rupture
Rupture Abdomen Aorta Aneurysm	Rupture Abdominal Aortic Aneurysm
Ruptured Abdomen Aneurysm	Ruptured Abdomen Aorta
Ruptured Abdomen Aortic	Ruptured Abdominal Aneurysm
Ruptured Abdominal Aorta	Ruptured Abdominal Aortic
Ruptured Aorta Abdominalis Aneurysm	False Abdomen Aorta Aneurysm Ruptured
False Abdominal Aortic Aneurysm Ruptured	False Abdominal Aorta Aneurysm Ruptured
False Abdomen Aortic Aneurysm Ruptured

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS00768	ANXA8 Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Mus musculus	ANXA8	MGD	MGI:1201374
Rattus norvegicus	ANXA8	RGD	RGD:1307719

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