Cir1 - corepressor interacting with RBPJ, 1 Gene

Also Known as Cir; Cicr; 1700023B02Rik; 2810021A19Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 66935

Summary

Predicted to enable histone deacetylase binding activity; protein kinase binding activity; and transcription corepressor activity. Acts upstream of or within in utero embryonic development. Predicted to be located in nuclear speck. Predicted to be part of protein-containing complex. Predicted to be active in nucleus. Predicted to colocalize with centrosome. Is expressed in genitourinary system and limb ectoderm. Orthologous to human CIR1 (corepressor interacting with RBPJ, CIR1). [provided by Alliance of Genome Resources, Apr 2022]

Cir1 Products (1)

mRNA Protein Name
NM_025854.4 NP_080130.2 corepressor interacting with RBPJ 1

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
15652350 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within in utero embryonic development IMP
IMP: Inferred from mutant phenotype
27996060 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

corepressor interacting with RBPJ 1

  • CBF1 interacting corepressor

Cir1 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
Cir1 Q9DA19 rp9 Mus musculus P97762
Y2H
15652350
Intra
Cir1 Q9DA19 rp9 Mus musculus P97762
Anti Tag CoIP
15652350
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (4)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS02720 CIR1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS15364 UBE2V1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS20706 Cir1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS27217 Cir1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Cir1 NCBI NCBI:9541